Anti-PITRM1 Antibody

$99.00$319.00

Reactivity: Human,Mouse,Rat
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PITRM1 Antibody (CSB-PA692283ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Presequence protease Antibody,mitochondrial Antibody,hPreP Antibody,Pitrilysin metalloproteinase 1 Antibody,Metalloprotease 1 Antibody,hMP1 Antibody,PITRM1 Antibody,KIAA1104 Antibody,MP1 Antibody

More alternative names for the antibody
hMP1 antibody|hPreP antibody|KIAA1104 antibody|Metalloprotease 1 antibody|MGC138192 antibody|MGC141929 antibody|mitochondrial antibody|MP1 antibody|Pitrilysin metallopeptidase 1 antibody|Pitrilysin metalloproteinase 1 antibody|PITRM 1 antibody|PITRM1 antibody|PreP antibody|PreP peptidasome antibody|PREP_HUMAN antibody|Presequence protease antibody|Presequence protease mitochondrial antibody
Anti-PITRM1 antibody (ab111681)
Close sc-82316|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-PITRM1 Antibody

Catalogue No.

CSB-PA692283ESR2HU

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant human Presequence protease, mitochondrial protein (758-1037AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

117 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10531( Human), Entrez Gene:69617( Mouse), SwissProt:Q5JRX3( Human), SwissProt:Q8K411( Mouse), Unigene:528300( Human), Unigene:41933( Mouse)

Protein function

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. .

Protein tissue specificity

Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta. .

Protein sequence and domain

Belongs to the peptidase M16 family. PreP subfamily.

Protein post-translational modifications

The disulfide bond may lock the enzyme in a closed conformation under oxidized conditions, suggesting that it may participate in redox regulation of the enzyme.

Protein cellular localization

Mitochondrion matrix .

Research area

All research areas>Synthesis and Degradation>PITRM
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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