Anti-PLEKHF2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PLEKHF2 Antibody (CSB-PA884492ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Pleckstrin homology domain-containing family F member 2 Antibody,PH domain-containing family F member 2 Antibody,Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains Antibody,EAPF Antibody,PH and FYVE domain-containing protein 2 Antibody,Phafin-2 Antibody,Phafin2 Antibody,Zinc finger FYVE domain-containing protein 18 Antibody,PLEKHF2 Antibody,ZFYVE18 Antibody

More alternative names for the antibody
110070J07Rik antibody|AA673237 antibody|FLJ13187 antibody|PH and FYVE domain containing protein 2 antibody|PH and FYVE domain-containing protein 2 antibody|PH domain containing family F member 2 antibody|PH domain-containing family F member 2 antibody|Phafin 2 antibody|Phafin-2 antibody|PHAFIN2 antibody|PKHF2_HUMAN antibody|pleckstrin homology domain containing, family F (with FYVE domain) member 2 antibody|pleckstrin homology domain containing, family F (with FYVE domain) member2 antibody|Pleckstrin homology domain-containing family F member 2 antibody|Plekhf2 antibody|ZFYVE18 antibody|Zinc finger FYVE domain containing protein 18 antibody|Zinc finger FYVE domain-containing protein 18 antibody
Anti-PLEKHF2 antibody (ab127047)
Close sc-87358|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PLEKHF2 Antibody

Catalogue No.

CSB-PA884492ESR1HU

Reactivity

Human

Immunogen

Recombinant human Pleckstrin homology domain-containing family F member 2 protein (1-249AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

27 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:79666( Human), SwissProt:Q9H8W4( Human), Unigene:29724( Human)

Protein function

May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467). .

Protein tissue specificity

Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells. .

Protein sequence and domain

The PH and FYVE domains may be important for TNF-induced localization to the endoplasmic reticulum and for enhanced cellular sensitivity to TNF-induced apoptosis (PubMed:18288467). The FYVE domain is important for binding to the endosomal membrane.

Protein cellular localization

Early endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum . Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots (PubMed:19995552). May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467). .

Research area

All research areas>Kinases and Phosphatases>PLEKHF
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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