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Rabbit Anti-PLEKHF2 Antibody (CSB-PA884492ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Pleckstrin homology domain-containing family F member 2 Antibody,PH domain-containing family F member 2 Antibody,Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains Antibody,EAPF Antibody,PH and FYVE domain-containing protein 2 Antibody,Phafin-2 Antibody,Phafin2 Antibody,Zinc finger FYVE domain-containing protein 18 Antibody,PLEKHF2 Antibody,ZFYVE18 AntibodyMore alternative names for the antibody
110070J07Rik antibody|AA673237 antibody|FLJ13187 antibody|PH and FYVE domain containing protein 2 antibody|PH and FYVE domain-containing protein 2 antibody|PH domain containing family F member 2 antibody|PH domain-containing family F member 2 antibody|Phafin 2 antibody|Phafin-2 antibody|PHAFIN2 antibody|PKHF2_HUMAN antibody|pleckstrin homology domain containing, family F (with FYVE domain) member 2 antibody|pleckstrin homology domain containing, family F (with FYVE domain) member2 antibody|Pleckstrin homology domain-containing family F member 2 antibody|Plekhf2 antibody|ZFYVE18 antibody|Zinc finger FYVE domain containing protein 18 antibody|Zinc finger FYVE domain-containing protein 18 antibody
Anti-PLEKHF2 antibody (ab127047)
Anti-PLEKHF2 antibody (ab127047)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Pleckstrin homology domain-containing family F member 2 protein (1-249AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=79666" target="_blank">Entrez Gene:79666( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q9H8W4" target="_blank">SwissProt:Q9H8W4( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=29724" target="_blank">Unigene:29724( Human)</a>
|Protein function|| |
May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467). .
|Protein tissue specificity|| |
Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells. .
|Protein sequence and domain|| |
The PH and FYVE domains may be important for TNF-induced localization to the endoplasmic reticulum and for enhanced cellular sensitivity to TNF-induced apoptosis (PubMed:18288467). The FYVE domain is important for binding to the endosomal membrane.
|Protein cellular localization|| |
Early endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum . Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots (PubMed:19995552). May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467). .
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Kinases-and-Phosphatases/">Kinases and Phosphatases</a>><a href="https://antibodyplus.com/product-tag/PLEKHF/">PLEKHF</a><br><a href="https://antibodyplus.com/product-tag/Kinases-and-Phosphatases/"> (View all antibody categories related to Kinases and Phosphatases)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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