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Rabbit Anti-PLXNB2 Antibody (CSB-PA018223ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Plexin-B2 Antibody,MM1 Antibody,PLXNB2 Antibody,KIAA0315 AntibodyMore alternative names for the antibody
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Plexin-B2 protein (1080-1200AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity). .
|Protein sequence and domain|| |
Belongs to the plexin family.
|Protein cellular localization|| |
Cell membrane ; Single-pass type I membrane protein .
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CUSABIO BIOTECH CO.
|Product type|| |
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