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Rabbit Anti-PPIL2 Antibody (CSB-PA621661ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Peptidyl-prolyl cis-trans isomerase-like 2Curated Antibody,CYC4 Antibody,PPIL2 AntibodyMore alternative names for the antibody
FLJ39930 antibody|CYC4 antibody|Cyclophilin 60 antibody|Cyclophilin 60kDa antibody|Cyclophilin like protein Cyp 60 antibody|Cyclophilin-60 antibody|Cyclophilin-like protein Cyp-60 antibody|CYP60 antibody|hCyP 60 antibody|MGC33174 antibody|MGC787 antibody|Peptidyl prolyl cis trans isomerase like 2 antibody|Peptidyl-prolyl cis-trans isomerase-like 2 antibody|Peptidylprolyl cis trans isomerase antibody|Peptidylprolyl isomerase cyclophilin like 2 antibody|PPIase antibody|PPIL2 antibody|PPIL2_HUMAN antibody|Rotamase antibody|Rotamase PPIL2 antibody
Anti-PPIL2 antibody (ab98925)
Anti-PPIL2 antibody (ab98925)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Peptidyl-prolyl cis-trans isomerase-like 2 protein (1-260AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:23759( Human), Entrez Gene:66053( Mouse), Entrez Gene:360746( Rat), Omim:607588( Human), SwissProt:Q13356( Human), SwissProt:Q9D787( Mouse), Unigene:438587( Human), Unigene:517436( Human), Unigene:253614( Mouse)
|Protein function|| |
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins (By similarity). May also function as a chaperone, playing a role in transport to the cell membrane of BSG for instance (PubMed:15946952). May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating ‘Lys-48’-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423). .
|Protein tissue specificity|| |
Highest expression in thymus, pancreas and testis. Also detected in heart, placenta, lung, liver, skeletal muscle, kidney, spleen, prostate, ovary, small intestine and colon. Poorly detected in brain and leukocytes. Strong protein expression in lymph node (cortical, paracortical and medullar regions), thyroid (follicular epithelial cells), testis (developing spermatozoa), stomach (cells lining the gastric pit), pancreas, kidney (proximal and distal-tubule cells and collecting duct cells but not in glomeruli), endometrium and colon (goblet cells). Moderate protein expression in spleen, prostate (epithelium and squamous cell carcinomas), placenta and adrenal gland. Weak protein expression in liver, heart, breast, ovary, and lung. No protein expression in brain and bladder. High protein expression in most lymphomas and melanomas. .
|Protein sequence and domain|| |
Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
|Protein cellular localization|| |
Nucleus . Note=May also localize to the cytoplasm and the cell membrane. .
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CUSABIO BIOTECH CO.
|Product type|| |
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