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Rabbit Anti-PPP1R3A Antibody (CSB-PA613701DSR1HU)
Supplier: CUSABIO BIOTECH CO.
Protein phosphatase 1 regulatory subunit 3A Antibody,Protein phosphatase 1 glycogen-associated regulatory subunit Antibody,Protein phosphatase type-1 glycogen targeting subunit Antibody,RG1 Antibody,PPP1R3A Antibody,PP1G AntibodyMore alternative names for the antibody
Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle antibody|Glycogen associated regulatory subunit of protein phosphatase 1 antibody|GM antibody|PP1G antibody|PPP1R3 antibody|PPP1R3A antibody|PPR3A_HUMAN antibody|Protein phosphatase 1 glycogen-associated regulatory subunit antibody|Protein phosphatase 1 glycogen-targeting subunit, muscle antibody|Protein phosphatase 1 regulatory subunit 3A antibody|Protein phosphatase 1 regulatory subunit GM antibody|protein phosphatase 1, regulatory (inhibitor) subunit 3A antibody|Protein phosphatase 1, regulatory subunit 3 antibody|Protein phosphatase type-1 glycogen targeting subunit antibody|RG1 antibody|Serine /threonine specific protein phosphatase antibody|Type 1 protein phosphatase skeletal muscle glycogen targeting subunit antibody
Anti-PPP1R3A antibody (ab137903)
Anti-PPP1R3A antibody (ab137903)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Protein phosphatase 1 regulatory subunit 3A protein (900-1080AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5506" target="_blank">Entrez Gene:5506( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/600917" target="_blank">Omim:600917( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q16821" target="_blank">SwissProt:Q16821( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=458309" target="_blank">Unigene:458309( Human)</a>
|Protein function|| |
Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase (By similarity). .
|Protein tissue specificity|| |
Skeletal muscle and heart. .
|Involvement in disease|| |
Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853]: A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
|Protein sequence and domain|| |
The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
|Protein post-translational modifications|| |
Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase. .
|Protein cellular localization|| |
Membrane ; Single-pass membrane protein .
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Kinases-and-Phosphatases/">Kinases and Phosphatases</a>><a href="https://antibodyplus.com/product-tag/PPP/">PPP</a><br><a href="https://antibodyplus.com/product-tag/Kinases-and-Phosphatases/"> (View all antibody categories related to Kinases and Phosphatases)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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