Anti-PRKAB2 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PRKAB2 Antibody (CSB-PA527326ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

AMPK subunit beta-2 Antibody,PRKAB2 Antibody

More alternative names for the antibody
5′ AMP activated protein kinase beta 2 subunit antibody|5′ AMP activated protein kinase subunit beta 2 antibody|5”-AMP-activated protein kinase subunit beta-2 antibody|AAKB2_HUMAN antibody|AMP activated protein kinase beta 2 non catalytic subunit antibody|AMPK beta 2 antibody|AMPK beta 2 chain antibody|AMPK subunit beta 2 antibody|AMPK subunit beta-2 antibody|MGC61468 antibody|PRKAB 2 antibody|Prkab2 antibody|Protein kinase AMP activated beta 2 non catalytic subunit antibody
Anti-AMPK beta 2 antibody [MM0963-7T21] (ab211668)
Close sc-100358|sc-376752|sc-19136|sc-19137|sc-376897|sc-20164|

Recommended applications: ELISA, WB

Recommended dilution: Recommended dilution:WB:1:500-2000

Recommended protocols: check protocols

Name

Anti-PRKAB2 Antibody

Catalogue No.

CSB-PA527326ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human 5′-AMP-activated protein kinase subunit beta-2 protein (1-272AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

Recommended dilution:WB:1:500-2000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

30 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5565( Human), Entrez Gene:108097( Mouse), Entrez Gene:64562( Rat), Omim:602741( Human), SwissProt:O43741( Human), SwissProt:Q6PAM0( Mouse), SwissProt:Q9QZH4( Rat), Unigene:50732( Human), Unigene:31175( Mouse), Unigene:207202( Rat)

Protein function

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Protein sequence and domain

Belongs to the 5′-AMP-activated protein kinase beta subunit family.

Protein post-translational modifications

Phosphorylated when associated with the catalytic subunit (PRKAA1 or PRKAA2). Phosphorylated by ULK1 and ULK2; leading to negatively regulate AMPK activity and suggesting the existence of a regulatory feedback loop between ULK1, ULK2 and AMPK. .

Research area

All research areas>Kinases and Phosphatases>AMPK
(View all antibody categories related to Kinases and Phosphatases)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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