Anti-PROK2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-PROK2 Antibody (CSB-PA875716ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Prokineticin-2 Antibody,PK2 Antibody,Protein Bv8 homolog Antibody,PROK2 Antibody,BV8 Antibody

More alternative names for the antibody
BV8 antibody|Bv8 homolog antibody|MIT1 antibody|PK2 antibody|PROK2 antibody|PROK2_HUMAN antibody|Prokineticin-2 antibody|Protein Bv8 homolog antibody
Anti-Prokineticin 2 antibody (ab76747)
Close sc-48069|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PROK2 Antibody

Catalogue No.

CSB-PA875716ESR2HU

Reactivity

Human

Immunogen

Recombinant human Prokineticin-2 protein (20-129AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

14 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:60675( Human), Entrez Gene:50501( Mouse), Entrez Gene:192206( Rat), Omim:607002( Human), SwissProt:Q9HC23( Human), SwissProt:Q9QXU7( Mouse), SwissProt:Q8R413( Rat), Unigene:528665( Human), Unigene:87365( Mouse), Unigene:211872( Rat)

Protein function

May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.

Protein tissue specificity

Expressed in the testis and, at low levels, in the small intestine.

Involvement in disease

Hypogonadotropic hypogonadism 4 with or without anosmia (HH4) [MIM:610628]: A disorder characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. In some cases, it is associated with non-reproductive phenotypes, such as anosmia, cleft palate, and sensorineural hearing loss. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In the presence of anosmia, idiopathic hypogonadotropic hypogonadism is referred to as Kallmann syndrome, whereas in the presence of a normal sense of smell, it has been termed normosmic idiopathic hypogonadotropic hypogonadism (nIHH). . Note=The disease is caused by mutations affecting distinct genetic loci, including the gene represented in this entry. The genetics of hypogonadotropic hypogonadism involves various modes of transmission. Oligogenic inheritance has been reported in some patients carrying mutations in PROK2 as well as in other HH-associated genes including PROKR2 (PubMed:23643382). .

Protein sequence and domain

Belongs to the AVIT (prokineticin) family.

Protein cellular localization

Secreted.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!