Anti-PTPRB Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PTPRB Antibody (CSB-PA019048ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Receptor-type tyrosine-protein phosphatase beta Antibody,Protein-tyrosine phosphatase beta Antibody,R-PTP-beta Antibody,Vascular endothelial protein tyrosine phosphatase Antibody,VE-PTP Antibody,PTPRB Antibody,PTPB Antibody

More alternative names for the antibody

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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PTPRB Antibody

Catalogue No.

CSB-PA019048ESR2HU

Reactivity

Human

Immunogen

Recombinant human Receptor-type tyrosine-protein phosphatase beta protein (1758-1997AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

224 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Protein function

Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin (By similarity). .

Protein sequence and domain

Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

Protein cellular localization

Membrane ; Single-pass type I membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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