Anti-PTPRJ Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PTPRJ Antibody (CSB-PA613274ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Receptor-type tyrosine-protein phosphatase eta Antibody,Protein-tyrosine phosphatase eta Antibody,R-PTP-eta Antibody,Density-enhanced phosphatase 1 Antibody,DEP-1 Antibody,HPTP eta Antibody,Protein-tyrosine phosphatase receptor type J Antibody,R-PTP-J Antibody,CD148 Antibody,PTPRJ Antibody,DEP1 Antibody

More alternative names for the antibody
CD 148 antibody|CD148 antibody|CD148 antigen antibody|Density enhanced phosphatase 1 antibody|Density-enhanced phosphatase 1 antibody|DEP 1 antibody|DEP-1 antibody|HPTP eta antibody|HPTPeta antibody|Human density enhanced phosphatase 1 antibody|Protein tyrosine phosphatase eta antibody|Protein tyrosine phosphatase receptor type J antibody|Protein tyrosine phosphatase receptor type J polypeptide antibody|Protein-tyrosine phosphatase eta antibody|Protein-tyrosine phosphatase receptor type J antibody|PTPJ antibody|Ptprj antibody|PTPRJ_HUMAN antibody|R PTP Eta antibody|R-PTP-eta antibody|R-PTP-J antibody|Receptor type tyrosine protein phosphatase eta antibody|Receptor-type tyrosine-protein phosphatase eta antibody|SCC 1 antibody|SCC1 antibody|susceptibility to colon cancer 1, mouse, homolog of antibody
Anti-DEP1 antibody (ab202958)
Close sc-13800|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PTPRJ Antibody

Catalogue No.

CSB-PA613274ESR1HU

Reactivity

Human

Immunogen

Recombinant human Receptor-type tyrosine-protein phosphatase eta protein (140-370AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

145 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5795( Human), Entrez Gene:19271( Mouse), Entrez Gene:29645( Rat), Omim:600925( Human), SwissProt:Q12913( Human), SwissProt:Q64455( Mouse), Unigene:318547( Human), Unigene:330393( Mouse), Unigene:10278( Rat)

Protein function

Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling. .

Protein tissue specificity

Expressed in the promyelocytic cell line HL-60, the granulocyte-macrophage colony-stimulating factor-dependent leukemic cell line F-36P, and the IL3 and erythropoietin-dependent leukemic cell line F-36E. Expressed predominantly in epithelial cells and lymphocytes. Enhanced expression at high cell density. .

Protein sequence and domain

Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

Protein post-translational modifications

N- and O-glycosylated. .

Protein cellular localization

Cell membrane; Single-pass type I membrane protein. Cell projection, ruffle membrane . Cell junction. Note=After T-cell stimulation, it is temporarily excluded from immunological synapses.

Research area

All research areas>Kinases and Phosphatases>DEP
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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