Anti-PTRH2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PTRH2 Antibody (CSB-PA837133ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

PTH 2 Antibody,Bcl-2 inhibitor of transcription 1 Antibody,PTRH2 Antibody,BIT1 Antibody, PTH2 Antibody,CGI-147 Antibody

More alternative names for the antibody
Bcl 2 inhibitor of transcription 1 antibody|Bcl-2 inhibitor of transcription 1 antibody|BIT 1 antibody|BIT1 antibody|CGI 147 antibody|CGI147 antibody|mitochondrial antibody|Peptidyl tRNA hydrolase 2 mitochondrial antibody|Peptidyl-tRNA hydrolase 2 antibody|PTH 2 antibody|PTH2 antibody|PTH2_HUMAN antibody|PTRH 2 antibody|PTRH2 antibody
Anti-PTRH2 antibody (ab36990)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PTRH2 Antibody

Catalogue No.

CSB-PA837133ESR1HU

Reactivity

Human

Immunogen

Recombinant human Peptidyl-tRNA hydrolase 2, mitochondrial protein (40-179AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

19 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:51651( Human), Entrez Gene:217057( Mouse), Entrez Gene:287593( Rat), Omim:608625( Human), SwissProt:Q9Y3E5( Human), SwissProt:Q8R2Y8( Mouse), Unigene:12677( Human), Unigene:24868( Mouse), Unigene:13456( Rat)

Protein function

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. .; Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1. .

Involvement in disease

Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset (IMNEPD) [MIM:616263]: A progressive multisystem disease characterized by a variety of neurologic, endocrine, and, in some patients, pancreatic features. Variable clinical symptoms include global developmental delay, hypotonia, hearing loss, ataxia, hyporeflexia, facial dysmorphism, hypothyroidism, and pancreatic insufficiency. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the PTH2 family.

Protein post-translational modifications

Ubiquitinated by PARK2 during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. .

Protein cellular localization

Mitochondrion.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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