Anti-RAC3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-RAC3 Antibody (CSB-PA019249ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ras-related C3 botulinum toxin substrate 3 Antibody,p21-Rac3 Antibody,RAC3 Antibody

More alternative names for the antibody
OTTMUSP00000004488 antibody|Rho family small GTP binding protein Rac3 antibody|RP23-84C12.18 antibody
Anti-RAC3 antibody [EPR6679(B)] (ab124943)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-RAC3 Antibody

Catalogue No.

CSB-PA019249ESR1HU

Reactivity

Human

Immunogen

Recombinant human Ras-related C3 botulinum toxin substrate 3 protein (1-192AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

21 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5881( Human), Entrez Gene:170758( Mouse), Omim:602050( Human), SwissProt:P60763( Human), SwissProt:P60764( Mouse), Unigene:45002( Human), Unigene:34008( Mouse)

Protein function

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner. .

Protein tissue specificity

Highest levels in brain, also detected in heart, placenta and pancreas.

Protein sequence and domain

Belongs to the small GTPase superfamily. Rho family.

Protein post-translational modifications

(Microbial infection) Glycosylated at Tyr-32 by Photorhabdus asymbiotica toxin PAU_02230. Mono-O-GlcNAcylation by PAU_02230 inhibits downstream signaling by an impaired interaction with diverse regulator and effector proteins of Rac and leads to actin disassembly. .

Protein cellular localization

Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton. Note=Membrane-associated when activated. Colocalizes with NRBP to endomembranes and at the cell periphery in lamellipodia. Colocalized with CIB1 in the perinuclear area and at the cell periphery.

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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