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Rabbit Anti-RAD1 Antibody (CSB-PA019252ESR1HU)
Supplier: CUSABIO BIOTECH CO.
hRAD1 Antibody,DNA repair exonuclease rad1 homolog Antibody,Rad1-like DNA damage checkpoint protein Antibody,RAD1 Antibody,REC1 AntibodyMore alternative names for the antibody
Cell cycle checkpoint protein Hrad1 antibody|Cell cycle checkpoint protein Rad 1 A / B antibody|Cell cycle checkpoint protein RAD1 antibody|Checkpoint control protein HRAD1 antibody|Checkpoint control protein RAD1 antibody|DNA repair exonuclease antibody|DNA repair exonuclease rad1 antibody|DNA repair exonuclease rad1 homolog antibody|DNA repair exonuclease REC1 antibody|DNA repair protein RAD1 antibody|EC 22.214.171.124 antibody|Exonuclease homolog RAD1 antibody|GTP-binding protein RAD antibody|hRAD 1 antibody|hRAD1 antibody|MGC77779 antibody|RAD 1 antibody|RAD antibody|RAD1 antibody|RAD1 homolog (S. pombe) antibody|RAD1 homolog antibody|Rad1 like DNA damage checkpoint antibody|Rad1 like DNA damage checkpoint protein antibody|RAD1, S. pombe, homolog of antibody|Rad1-like DNA damage checkpoint protein antibody|RAD1_HUMAN antibody|Ras associated with diabetes antibody|REC 1 antibody|REC1 antibody|RRAD antibody
Anti-Rad1 antibody (ab168397)
Anti-Rad1 antibody (ab168397)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Cell cycle checkpoint protein RAD1 protein (1-282AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3′-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. Isoform 1 possesses 3′->5′ double stranded DNA exonuclease activity. .
|Protein tissue specificity|| |
Expressed in testis, uterus, bladder, spleen, ovaries, lung, brain and muscle (at protein level). .
|Protein sequence and domain|| |
Belongs to the rad1 family.
|Protein cellular localization|| |
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CUSABIO BIOTECH CO.
|Product type|| |
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