Anti-RAD51D Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-RAD51D Antibody (CSB-PA019268ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

R51H3 Antibody,RAD51 homolog D Antibody,RAD51-like protein 3 Antibody,TRAD Antibody,RAD51D Antibody,RAD51L3 Antibody

More alternative names for the antibody
BROVCA4 antibody|DNA repair protein RAD51 homolog 4 antibody|HsTRAD antibody|OTTHUMP00000163851 antibody|OTTHUMP00000163852 antibody|OTTHUMP00000163853 antibody|R51H3 antibody|RA51D_HUMAN antibody|RAD51 homolog D (S. cerevisiae) antibody|RAD51 homolog D antibody|RAD51 like 3 (S. cerevisiae) antibody|RAD51 paralog D antibody|RAD51, S. cerevisiae, homolog of, D antibody|RAD51-like protein 3 antibody|Rad51l3 antibody|Recombination repair protein antibody|S. cerevisiae RAD51-like 3 antibody|TRAD antibody
Anti-Rad51D antibody [EPR16205] (ab202063)
Close sc-53431|sc-53432|sc-398819|sc-366363|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-RAD51D Antibody

Catalogue No.

CSB-PA019268ESR1HU

Reactivity

Human

Immunogen

Recombinant human DNA repair protein RAD51 homolog 4 protein (1-328AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

35 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5892( Human), Entrez Gene:303375( Rat), Omim:602954( Human), SwissProt:O75771( Human), Unigene:631757( Human), Unigene:206266( Rat)

Protein function

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM. .

Protein tissue specificity

Expressed in colon, prostate, spleen, testis, ovary, thymus and small intestine. Weakly expressed in leukocytes.

Involvement in disease

Breast-ovarian cancer, familial, 4 (BROVCA4) [MIM:614291]: A condition associated with familial predisposition to cancer of the breast and ovaries. Characteristic features in affected families are an early age of onset of breast cancer (often before age 50), increased chance of bilateral cancers (cancer that develop in both breasts, or both ovaries, independently), frequent occurrence of breast cancer among men, increased incidence of tumors of other specific organs, such as the prostate. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the RecA family. RAD51 subfamily.

Protein cellular localization

Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, telomere.

Research area

All research areas>Tumor Suppressor/Apoptosis>Rad
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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