Anti-RANBP3 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-RANBP3 Antibody (CSB-PA867162DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ran-binding protein 3 Antibody,RanBP3 Antibody,RANBP3 Antibody

More alternative names for the antibody
DKFZp586I1520 antibody|Ran binding protein 3 antibody|Ran-binding protein 3 antibody|RANB3_HUMAN antibody|RanBP3 antibody
Anti-RanBP3 antibody [EPR5088(2)] (ab134052)
Close sc-136055|sc-47351|sc-373678|sc-377253|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-RANBP3 Antibody

Catalogue No.

CSB-PA867162DSR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Ran-binding protein 3 protein (1-250AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

60 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8498( Human), Entrez Gene:71810( Mouse), Omim:603327( Human), SwissProt:Q9H6Z4( Human), SwissProt:Q9CT10( Mouse), Unigene:531752( Human), Unigene:29608( Mouse), Unigene:469805( Mouse)

Protein function

Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. .

Protein tissue specificity

Widely expressed with high levels in testis and heart. .

Protein cellular localization

Cytoplasm . Nucleus .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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