Anti-RASA4 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-RASA4 Antibody (CSB-PA019349ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ras GTPase-activating protein 4 Antibody,Calcium-promoted Ras inactivator Antibody,Ras p21 protein activator 4 Antibody,RasGAP-activating-like protein 2 Antibody,RASA4 Antibody,CAPRI Antibody,GAPL Antibody,KIAA0538 Antibody

More alternative names for the antibody
Ca2+ promoted Ras inactivator antibody|Calcium promoted Ras inactivator antibody|CAPRI antibody|GAPL antibody|GTPase activating protein like antibody|KIAA0538 antibody|MGC131890 antibody|Ras GTPase activating protein 4 antibody|RAS p21 protein activator 4 antibody|RasGAP activating like protein 2 antibody
Anti-RASA4 antibody [EPR10515] (ab157190)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-RASA4 Antibody

Catalogue No.

CSB-PA019349ESR2HU

Reactivity

Human

Immunogen

Recombinant human Ras GTPase-activating protein 4 protein (60-290AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

90 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10156( Human), Entrez Gene:54153( Mouse), Entrez Gene:288589( Rat), Omim:607943( Human), SwissProt:O43374( Human), SwissProt:Q6PFQ7( Mouse), Unigene:696339( Human), Unigene:290655( Mouse), Unigene:1366( Rat)

Protein function

Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. .

Protein tissue specificity

Widely expressed. .

Protein sequence and domain

The PH domain does not bind phosphatidylinositol 4,5-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate. This lack of binding activity is due to Leu-592, compared to Arg found in other family members.

Protein cellular localization

Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein . Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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