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Rabbit Anti-RASSF5 Antibody (CSB-PA819906ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Ras association domain-containing protein 5 Antibody,New ras effector 1 Antibody,Regulator for cell adhesion and polarization enriched in lymphoid tissues Antibody,RAPL Antibody,RASSF5 Antibody,NORE1 Antibody,RAPL AntibodyMore alternative names for the antibody
Maxp 1 antibody|MAXP1 antibody|MGC10823 antibody|MGC17344 antibody|New ras effector 1 antibody|NORE 1 antibody|NORE1A antibody|NORE1B antibody|Novel Ras effector 1 antibody|RAP1 Binding Protein antibody|RAPL antibody|Ras association (RalGDS/AF 6) domain family 5 antibody|Ras association (RalGDS/AF 6) domain family member 5 antibody|Ras association domain containing family protein 5 antibody|Ras association domain-containing protein 5 antibody|Ras effector like protein antibody|RASF5_HUMAN antibody|RASSF 3 antibody|RASSF 5 antibody|RASSF3 antibody|RASSF5 antibody|Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody|Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody|Tumor suppressor RASSF3 antibody
Anti-NORE1 antibody (ab22770)
Anti-NORE1 antibody (ab22770)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Ras association domain-containing protein 5 protein (1-265AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:83593( Human), Entrez Gene:54354( Mouse), Entrez Gene:54355( Rat), Omim:607020( Human), SwissProt:Q8WWW0( Human), SwissProt:Q5EBH1( Mouse), SwissProt:O35141( Rat), Unigene:497579( Human), Unigene:248291( Mouse), Unigene:36106( Rat)
|Protein function|| |
Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis. .
|Protein tissue specificity|| |
Widely expressed. Frequently down-regulated in lung tumor cell lines and primary lung tumors. .
|Protein cellular localization|| |
Cytoplasm. Cytoplasm, cytoskeleton. Note=Isoform 2 is mainly located in the perinuclear region of unstimulated primary T-cells. Upon stimulation translocates to the leading edge and colocalizes with ITGAL/LFA-1 in the peripheral zone of the immunological synapse. Isoform 2 is localized to growing microtubules in vascular endothelial cells and is dissociated from microtubules by activated RAP1A.
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CUSABIO BIOTECH CO.
|Product type|| |
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