Anti-RASSF5 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-RASSF5 Antibody (CSB-PA819906ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ras association domain-containing protein 5 Antibody,New ras effector 1 Antibody,Regulator for cell adhesion and polarization enriched in lymphoid tissues Antibody,RAPL Antibody,RASSF5 Antibody,NORE1 Antibody,RAPL Antibody

More alternative names for the antibody
Maxp 1 antibody|MAXP1 antibody|MGC10823 antibody|MGC17344 antibody|New ras effector 1 antibody|NORE 1 antibody|NORE1A antibody|NORE1B antibody|Novel Ras effector 1 antibody|RAP1 Binding Protein antibody|RAPL antibody|Ras association (RalGDS/AF 6) domain family 5 antibody|Ras association (RalGDS/AF 6) domain family member 5 antibody|Ras association domain containing family protein 5 antibody|Ras association domain-containing protein 5 antibody|Ras effector like protein antibody|RASF5_HUMAN antibody|RASSF 3 antibody|RASSF 5 antibody|RASSF3 antibody|RASSF5 antibody|Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody|Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody|Tumor suppressor RASSF3 antibody
Anti-NORE1 antibody (ab22770)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-RASSF5 Antibody

Catalogue No.

CSB-PA819906ESR1HU

Reactivity

Human

Immunogen

Recombinant human Ras association domain-containing protein 5 protein (1-265AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

47 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:83593( Human), Entrez Gene:54354( Mouse), Entrez Gene:54355( Rat), Omim:607020( Human), SwissProt:Q8WWW0( Human), SwissProt:Q5EBH1( Mouse), SwissProt:O35141( Rat), Unigene:497579( Human), Unigene:248291( Mouse), Unigene:36106( Rat)

Protein function

Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis. .

Protein tissue specificity

Widely expressed. Frequently down-regulated in lung tumor cell lines and primary lung tumors. .

Protein cellular localization

Cytoplasm. Cytoplasm, cytoskeleton. Note=Isoform 2 is mainly located in the perinuclear region of unstimulated primary T-cells. Upon stimulation translocates to the leading edge and colocalizes with ITGAL/LFA-1 in the peripheral zone of the immunological synapse. Isoform 2 is localized to growing microtubules in vascular endothelial cells and is dissociated from microtubules by activated RAP1A.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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