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Rabbit Anti-RDH12 Antibody (CSB-PA842727ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Retinol dehydrogenase 12 Antibody,All-trans and 9-cis retinol dehydrogenase Antibody,Short chain dehydrogenase/reductase family 7C member 2 Antibody,RDH12 Antibody,SDR7C2 AntibodyMore alternative names for the antibody
All trans and 9 cis retinol dehydrogenase antibody|All-trans and 9-cis retinol dehydrogenase antibody|LCA 3 antibody|LCA13 antibody|LCA3 antibody|RDH 12 antibody|RDH12 antibody|RDH12_HUMAN antibody|Retinol dehydrogenase 12 (all trans/9 cis/11 cis) antibody|Retinol dehydrogenase 12 all trans and 9 cis antibody|Retinol dehydrogenase 12 antibody|RP53 antibody|SDR7C2 antibody|Short chain dehydrogenase/reductase family 7C member 2 antibody
Anti-RDH12 antibody (ab173449)
Anti-RDH12 antibody (ab173449)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Retinol dehydrogenase 12 protein (182-316AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments. .
|Protein tissue specificity|| |
Widely expressed, mostly in eye, kidney, brain, skeletal muscle and stomach.
|Involvement in disease|| |
Leber congenital amaurosis 13 (LCA13) [MIM:612712]: A severe dystrophy of the retina, typically becoming evident in the first years of life. Visual function is usually poor and often accompanied by nystagmus, sluggish or near-absent pupillary responses, photophobia, high hyperopia and keratoconus. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Retinitis pigmentosa 53 (RP53) [MIM:612712]: A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
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CUSABIO BIOTECH CO.
|Product type|| |
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