Anti-REC8 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-REC8 Antibody (CSB-PA019535ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Meiotic recombination protein REC8 homolog Antibody,Cohesin Rec8p Antibody,REC8 Antibody,REC8L1 Antibody

More alternative names for the antibody
Cohesin Rec8p antibody|Human homolog of rad21 S. pombe antibody|Meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family antibody|Meiotic recombination protein REC8 homolog antibody|Meiotic recombination protein REC8-like 1 antibody|rec8 antibody|REC8 homolog (yeast) antibody|REC8 like 1 antibody|REC8_HUMAN antibody|Rec8p antibody|Recombination and sister chromatid cohesion protein homolog antibody
Anti-REC8 antibody [EPR16189] (ab192241)
Close sc-15154|sc-15152|sc-366993|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-REC8 Antibody

Catalogue No.

CSB-PA019535ESR2HU

Reactivity

Human

Immunogen

Recombinant human Meiotic recombination protein REC8 homolog protein (1-270AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

62 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9985( Human), Entrez Gene:56739( Mouse), Entrez Gene:290227( Rat), Omim:608193( Human), SwissProt:O95072( Human), SwissProt:Q8C5S7( Mouse), SwissProt:Q6AYJ4( Rat), Unigene:419259( Human), Unigene:23149( Mouse), Unigene:108612( Rat)

Protein function

Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity). .

Protein tissue specificity

Expressed in testis and thymus. Expressed in the B-cell lines WI-L2-NS and Namalwa (at protein level). .

Protein sequence and domain

Belongs to the rad21 family.

Protein post-translational modifications

Phosphorylated. .

Protein cellular localization

Nucleus . Chromosome . Chromosome, centromere . Note=In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II. Localised to centromeres and spindle poles in endopolyploid tumor cells. .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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