Anti-REEP1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-REEP1 Antibody (CSB-PA862045DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Receptor expression-enhancing protein 1 Antibody,REEP1 Antibody,C2orf23 Antibody

More alternative names for the antibody
C2orf23 antibody|Chromosome 2 open reading frame 23 antibody|FLJ13110 antibody|Receptor accessory protein 1 antibody|Receptor expression-enhancing protein 1 antibody|Reep1 antibody|REEP1_HUMAN antibody|SPG31 antibody
Anti-REEP1 antibody (ab105583)
Close sc-393242|sc-133401|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-REEP1 Antibody

Catalogue No.

CSB-PA862045DSR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Receptor expression-enhancing protein 1 protein (101-201AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

22 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:65055( Human), Entrez Gene:52250( Mouse), Entrez Gene:362384( Rat), Omim:609139( Human), SwissProt:Q9H902( Human), SwissProt:Q8BGH4( Mouse), SwissProt:D4A193( Rat), Unigene:368884( Human), Unigene:146332( Mouse)

Protein function

Required for endoplasmic reticulum (ER) network formation, shaping and remodeling; it links ER tubules to the cytoskeleton. May also enhance the cell surface expression of odorant receptors (PubMed:20200447). May play a role in long-term axonal maintenance (PubMed:24478229). .

Protein tissue specificity

Expressed in circumvallate papillae and testis. .

Involvement in disease

Spastic paraplegia 31, autosomal dominant (SPG31) [MIM:610250]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Neuronopathy, distal hereditary motor, 5B (HMN5B) [MIM:614751]: A disorder characterized by distal muscular atrophy mainly affecting the upper extremities, in contrast to other distal motor neuronopathies. These constitute a heterogeneous group of neuromuscular diseases caused by selective degeneration of motor neurons in the anterior horn of the spinal cord, without sensory deficit in the posterior horn. The overall clinical picture consists of a classical distal muscular atrophy syndrome in the legs without clinical sensory loss. The disease starts with weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs. Later on, weakness and atrophy may expand to the proximal muscles of the lower limbs and/or to the distal upper limbs. HMN5B is characterized by onset in the first or second decade of distal muscle weakness and atrophy, primarily affecting the intrinsic hand muscles, but also affecting the lower legs, resulting in abnormal gait and pes cavus. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the DP1 family.

Protein cellular localization

Membrane . Mitochondrion membrane ; Multi-pass membrane protein . Endoplasmic reticulum . Note=Localizes to endoplasmic reticulum tubular network. .

Research area

All research areas>Transport and Trafficking>REEP
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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