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Rabbit Anti-RFX5 Antibody (CSB-PA019614ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Regulatory factor X 5 Antibody,RFX5 AntibodyMore alternative names for the antibody
DNA binding protein RFX 5 antibody|DNA binding protein RFX5 antibody|DNA-binding protein RFX5 antibody|Influences HLA class II expression antibody|Regulatory factor X 5 antibody|Regulatory factor X subunit 5 antibody|Regulatory factor X, 5 (influences HLA class II expression) antibody|RFX 5 antibody|RFX5 antibody|Rfx5 protein antibody|RFX5_HUMAN antibody
Anti-RFX5 antibody (ab9255)
Anti-RFX5 antibody (ab9255)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human DNA-binding protein RFX5 protein (367-616AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.
|Protein tissue specificity|| |
|Involvement in disease|| |
Bare lymphocyte syndrome 2 (BLS2) [MIM:209920]: A severe combined immunodeficiency disease with early onset. It is characterized by a profound defect in constitutive and interferon-gamma induced MHC II expression, absence of cellular and humoral T-cell response to antigen challenge, hypogammaglobulinemia and impaired antibody production. The consequence include extreme susceptibility to viral, bacterial and fungal infections. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the RFX family. The N-terminus is required for dimer formation, association with RFXANK and RFXAP, assembly of the RFX complex, and for binding of this complex to its X box target site in the MHC-II promoter. The C-terminus mediates cooperative binding between the RFX complex and NF-Y.; The PxLPxI/L motif mediates interaction with ankyrin repeats of RFXANK.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
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CUSABIO BIOTECH CO.
|Product type|| |
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