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Rabbit Anti-RGS20 Antibody (CSB-PA019652ESR1HU)
Supplier: CUSABIO BIOTECH CO.
RGS20 Antibody,Gz-selective GTPase-activating protein Antibody,G(z)GAP Antibody,Gz-GAP Antibody,Regulator of G-protein signaling Z1 Antibody,Regulator of Gz-selective protein signaling 1 Antibody,RGS20 Antibody,RGSZ1 Antibody,ZGAP1 AntibodyMore alternative names for the antibody
G(z)GAP antibody|Gz selective GTPase activating protein antibody|Gz-GAP antibody|Gz-selective GTPase-activating protein antibody|HGNC:14600 antibody|Regulator of G protein signaling 20 antibody|Regulator of G-protein signaling 20 antibody|Regulator of G-protein signaling Z1 antibody|Regulator of Gz selective protein signaling 1 antibody|Regulator of Gz-selective protein signaling 1 antibody|RGS20 antibody|RGS20_HUMAN antibody|RGSZ1 antibody|ZGAP1 antibody
Anti-RGS20 antibody (ab77009)
Anti-RGS20 antibody (ab77009)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Regulator of G-protein signaling 20 protein (1-241AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8601" target="_blank">Entrez Gene:8601( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=58175" target="_blank">Entrez Gene:58175( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/607193" target="_blank">Omim:607193( Human)</a>, <a href="http://www.uniprot.org/uniprot/O76081" target="_blank">SwissProt:O76081( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q9QZB1" target="_blank">SwissProt:Q9QZB1( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=368733" target="_blank">Unigene:368733( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=103771" target="_blank">Unigene:103771( Mouse)</a>
|Protein function|| |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity). .
|Protein tissue specificity|| |
Isoform 5 is expressed in brain at high levels in the caudate nucleus and temporal lobe.
|Protein post-translational modifications|| |
Fatty acylated. Heavily palmitoylated in the cysteine string motif (By similarity). .; N- and O-glycosylated in synapsomal membranes. .; Serine phosphorylated in synapsomal membranes. .; Sumoylated with SUMO1 and SUMO2 in synaptosomes. The sumoylated forms act as a scaffold for sequestering mu-opioid receptor-activated G(alpha) subunits (By similarity). .
|Protein cellular localization|| |
Membrane; Lipid-anchor. Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm/cell membrane and the nucleus. Anchored to the membrane through palmitoylation. .
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CUSABIO BIOTECH CO.
|Product type|| |
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