Anti-RGS20 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-RGS20 Antibody (CSB-PA019652ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

RGS20 Antibody,Gz-selective GTPase-activating protein Antibody,G(z)GAP Antibody,Gz-GAP Antibody,Regulator of G-protein signaling Z1 Antibody,Regulator of Gz-selective protein signaling 1 Antibody,RGS20 Antibody,RGSZ1 Antibody,ZGAP1 Antibody

More alternative names for the antibody
G(z)GAP antibody|Gz selective GTPase activating protein antibody|Gz-GAP antibody|Gz-selective GTPase-activating protein antibody|HGNC:14600 antibody|Regulator of G protein signaling 20 antibody|Regulator of G-protein signaling 20 antibody|Regulator of G-protein signaling Z1 antibody|Regulator of Gz selective protein signaling 1 antibody|Regulator of Gz-selective protein signaling 1 antibody|RGS20 antibody|RGS20_HUMAN antibody|RGSZ1 antibody|ZGAP1 antibody
Anti-RGS20 antibody (ab77009)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-RGS20 Antibody

Catalogue No.

CSB-PA019652ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Regulator of G-protein signaling 20 protein (1-241AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

43 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8601( Human), Entrez Gene:58175( Mouse), Omim:607193( Human), SwissProt:O76081( Human), SwissProt:Q9QZB1( Mouse), Unigene:368733( Human), Unigene:103771( Mouse)

Protein function

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity). .

Protein tissue specificity

Isoform 5 is expressed in brain at high levels in the caudate nucleus and temporal lobe.

Protein post-translational modifications

Fatty acylated. Heavily palmitoylated in the cysteine string motif (By similarity). .; N- and O-glycosylated in synapsomal membranes. .; Serine phosphorylated in synapsomal membranes. .; Sumoylated with SUMO1 and SUMO2 in synaptosomes. The sumoylated forms act as a scaffold for sequestering mu-opioid receptor-activated G(alpha) subunits (By similarity). .

Protein cellular localization

Membrane; Lipid-anchor. Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm/cell membrane and the nucleus. Anchored to the membrane through palmitoylation. .

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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