Anti-RGS9 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-RGS9 Antibody (CSB-PA019662ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Regulator of G-protein signaling 9 Antibody,RGS9 Antibody,RGS9 Antibody

More alternative names for the antibody
PERRS antibody|R9AP antibody|Regulator of G protein signalling 9 antibody|Regulator of G-protein signaling 9 antibody|RGS9 antibody|RGS9_HUMAN antibody|RGS9L antibody
Anti-RGS9 antibody [EPR2873] (ab108975)
Close sc-377252|sc-8142|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-RGS9 Antibody

Catalogue No.

CSB-PA019662ESR1HU

Reactivity

Human

Immunogen

Recombinant human Regulator of G-protein signaling 9 protein (230-350AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

76 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8787( Human), Entrez Gene:19739( Mouse), Entrez Gene:29481( Rat), Omim:604067( Human), SwissProt:O75916( Human), SwissProt:O54828( Mouse), SwissProt:P49805( Rat), Unigene:664380( Human), Unigene:38548( Mouse), Unigene:10903( Rat)

Protein function

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity). .

Protein tissue specificity

Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors).

Involvement in disease

Prolonged electroretinal response suppression (PERRS) [MIM:608415]: Characterized by difficulty adjusting to sudden changes in luminance levels mediated by cones. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

In photoreceptor cells the DEP domain is essential for targeting RGS9 to the outer rod segments.

Protein post-translational modifications

Retinal isoform 3 is light-dependent phosphorylated at ‘Ser-478’. Phosphorylation is decreased by light exposition (By similarity). .

Protein cellular localization

Isoform 3: Membrane; Peripheral membrane protein. Note=Isoform 3 is targeted to the membrane via its interaction with RGS9BP. .

Research area

All research areas>Signaling Intermediates>R9AP
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!