Anti-RIC8A Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-RIC8A Antibody (CSB-PA878847ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Synembryn-A Antibody,Protein Ric-8A Antibody,RIC8A Antibody

More alternative names for the antibody
MGC104517 antibody|MGC131931 antibody|MGC148073 antibody|MGC148074 antibody|Protein Ric-8A antibody|resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) antibody|RIC8 antibody|RIC8A antibody|RIC8A_HUMAN antibody|Synembryn-A antibody
Anti-RIC8A antibody (ab194941)
Close sc-398962|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-RIC8A Antibody

Catalogue No.

CSB-PA878847ESR2HU

Reactivity

Human

Immunogen

Recombinant human Synembryn-A protein (362-531AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

59 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:60626( Human), Entrez Gene:101489( Mouse), Entrez Gene:293614( Rat), Omim:609146( Human), SwissProt:Q5E9J8( Cow), SwissProt:Q9NPQ8( Human), SwissProt:Q3TIR3( Mouse), SwissProt:Q5R8F5( Orangutan), SwissProt:Q80ZG1( Rat), Unigene:592292( Human), Unigene:281916( Mouse), Unigene:94796( Rat)

Protein function

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation. .

Protein sequence and domain

Belongs to the synembryn family.

Protein cellular localization

Cytoplasm . Cell membrane . Note=Colocalizes with RIC8A in CA2 hippocampal neurons. Colocalizes with GNAI1 and RGS14 at the plasma membrane (By similarity). .

Research area

All research areas>Signaling Intermediates>RIC
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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