No products in the cart.
Rabbit Anti-RICTOR Antibody (CSB-PA761396ESR1HU)
Supplier: CUSABIO BIOTECH CO.
AVO3 homolog Antibody,hAVO3 Antibody,RICTOR AntibodyMore alternative names for the antibody
AVO3 antibody|AVO3 homolog antibody|DKFZp686B11164 antibody|hAVO3 antibody|KIAA1999 antibody|Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae) antibody|mAVO3 antibody|MGC39830 antibody|PIA antibody|Pianissimo antibody|Rapamycin insensitive companion of mTOR antibody|Rapamycin-insensitive companion of mTOR antibody|Rictor antibody|RICTR antibody|RICTR_HUMAN antibody|RPTOR independent companion of MTOR complex 2 antibody|TORC2 specific protein AVO3 antibody
Anti-RICTOR antibody (ab70374)
Anti-RICTOR antibody (ab70374)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Rapamycin-insensitive companion of mTOR protein (1-245AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:461907( Chimpanzee), Entrez Gene:479356( Dog), Entrez Gene:101132782( Gorilla), Entrez Gene:253260( Human), Entrez Gene:78757( Mouse), Entrez Gene:100443248( Orangutan), Entrez Gene:694915( Rhesus monkey), Omim:609022( Human), SwissProt:Q6R327( Human), SwissProt:Q6QI06( Mouse), Unigene:407926( Human), Unigene:275811( Mouse)
|Protein function|| |
Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 ‘Ser-473’ phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on ‘Thr-308’ by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at ‘Ser-422’. mTORC2 also modulates the phosphorylation of PRKCA on ‘Ser-657’. Plays an essential role in embryonic growth and development. .
|Protein sequence and domain|| |
Belongs to the RICTOR family.
|Protein post-translational modifications|| |
Phosphorylated by MTOR; when part of mTORC2. Phosphorylated at Thr-1135 by RPS6KB1; phosphorylation of RICTOR inhibits mTORC2 and AKT1 signaling. .
AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.
CUSABIO BIOTECH CO.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: