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Rabbit Anti-ROM1 Antibody (CSB-PA344843ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Rod outer segment membrane protein 1 Antibody,ROSP1 Antibody,Tetraspanin-23 Antibody,Tspan-23 Antibody,ROM1 Antibody,TSPAN23 AntibodyMore alternative names for the antibody
Retinal outer segment membrane protein 1 antibody|Rod outer segment membrane protein 1 antibody|ROM antibody|ROM1 antibody|ROM1_HUMAN antibody|ROSP1 antibody|RP7 antibody|Tetraspanin 23 antibody|Tetraspanin-23 antibody|Tspan 23 antibody|Tspan-23 antibody|TSPAN23 antibody
Anti-ROM1 antibody (ab80507)
Anti-ROM1 antibody (ab80507)
Recommended applications: ELISA, WB
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Rod outer segment membrane protein 1 protein (126-263AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:6094( Human), Entrez Gene:19881( Mouse), Entrez Gene:309201( Rat), Omim:180721( Human), SwissProt:Q03395( Human), SwissProt:P32958( Mouse), SwissProt:Q5PPM7( Rat), Unigene:281564( Human), Unigene:426094( Mouse), Unigene:145021( Rat)
|Protein function|| |
May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.
|Protein tissue specificity|| |
Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.
|Involvement in disease|| |
Retinitis pigmentosa 7 (RP7) [MIM:608133]: A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. . Note=The disease may be caused by mutations affecting distinct genetic loci, including the gene represented in this entry. A digenic form of retinitis pigmentosa 7 results from a mutation in the PRPH2 gene and a null mutation of the ROM1 gene has been reported (PubMed:8202715). .
|Protein sequence and domain|| |
Belongs to the PRPH2/ROM1 family.
|Protein cellular localization|| |
Membrane; Multi-pass membrane protein.
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|Product type|| |
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