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Rabbit Anti-RSAD2 Antibody (CSB-PA848838ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Cytomegalovirus-induced gene 5 protein;Viperin;Virus inhibitory protein Antibody, endoplasmic reticulum-associated Antibody, interferon-inducible;RSAD2;CIG5 AntibodyMore alternative names for the antibody
2510004L01Rik antibody|cig 33 antibody|CIG 5 antibody|cig-33 antibody|CIG-5 antibody|CIG33 antibody|CIG5 antibody|Cytomegalovirus induced gene 5 protein antibody|Cytomegalovirus-induced gene 5 protein antibody|endoplasmic reticulum-associated antibody|interferon-inducible antibody|Radical S adenosyl methionine domain containing 2 antibody|Radical S-adenosyl methionine domain-containing protein 2 antibody|RSAD 2 antibody|Rsad2 antibody|RSAD2_HUMAN antibody|RSDA-2 antibody|VIG 1 antibody|vig1 antibody|Viperin antibody|Virus inhibitory protein antibody|virus inhibitory protein endoplasmic reticulum associated interferon inducible antibody
Anti-Viperin antibody (ab73864)
Anti-Viperin antibody (ab73864)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Radical S-adenosyl methionine domain-containing protein 2 protein (42-361AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:459006( Chimpanzee), Entrez Gene:609005( Dog), Entrez Gene:91543( Human), Entrez Gene:58185( Mouse), Entrez Gene:100190846( Orangutan), Entrez Gene:65190( Rat), Omim:607810( Human), SwissProt:Q8WXG1( Human), SwissProt:Q8CBB9( Mouse), SwissProt:Q5RCW8( Orangutan), SwissProt:O70600( Rat), Unigene:17518( Human), Unigene:24045( Mouse), Unigene:14882( Rat)
|Protein function|| |
Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphosphate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63′-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins. .
|Protein sequence and domain|| |
Belongs to the radical SAM superfamily. RSAD2 family. The N-terminal region (1-42) is necessary for its localization to the endoplasmic reticulum membrane and lipid droplet.
|Protein cellular localization|| |
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus . Endoplasmic reticulum . Lipid droplet . Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane. Note=Infection with human cytomegalovirus (HCMV) causes relocation to the Golgi apparatus and to cytoplasmic vacuoles which also contain HCMV proteins glycoprotein B and pp28. Interaction with human cytomegalovirus/HHV-5 protein vMIA/UL37 results in its relocalization from the endoplasmic reticulum to the mitochondria.
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CUSABIO BIOTECH CO.
|Product type|| |
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