Anti-SAP18 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-SAP18 Antibody (CSB-PA020695ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

18 kDa Sin3-associated polypeptide;2HOR0202;Cell growth-inhibiting gene 38 protein;Sin3-associated polypeptide p18;SAP18;GIG38 Antibody

More alternative names for the antibody
18 kDa Sin3-associated polypeptide antibody|2HOR0202 antibody|Cell growth-inhibiting gene 38 protein antibody|Histone deacetylase complex subunit SAP18 antibody|SAP18 antibody|SAP18_HUMAN antibody|Sin3-associated polypeptide p18 antibody
Anti-SAP18 antibody (ab31748)
Close sc-8473|sc-365377|sc-514365|sc-365376|sc-25377|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SAP18 Antibody

Catalogue No.

CSB-PA020695ESR2HU

Reactivity

Human

Immunogen

Recombinant human Histone deacetylase complex subunit SAP18 protein (2-153AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

17 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:615692( Cow), Entrez Gene:10284( Human), Entrez Gene:20220( Mouse), Entrez Gene:290284( Rat), Entrez Gene:393693( Zebrafish), Omim:602949( Human), SwissProt:Q3T022( Cow), SwissProt:O00422( Human), SwissProt:O55128( Mouse), Unigene:524899( Human), Unigene:30173( Mouse), Unigene:344671( Mouse), Unigene:74373( Rat)

Protein function

Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit mRNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits the formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. .

Protein tissue specificity

Ubiquitous.

Protein sequence and domain

Belongs to the SAP18 family.

Protein cellular localization

Nucleus . Cytoplasm . Nucleus speckle . Note=Shuttles between the nucleus and the cytoplasm (PubMed:16314458). Colocalizes with ACIN1 and SRSF2 in nuclear speckles (PubMed:20966198). .

Research area

All research areas>Transcription Regulators>SAP
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!