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Rabbit Anti-SCN3A Antibody (CSB-PA885761ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Sodium channel protein type 3 subunit alpha Antibody,Sodium channel protein brain III subunit alpha Antibody,Sodium channel protein type III subunit alpha Antibody,Voltage-gated sodium channel subtype III Antibody,Voltage-gated sodium channel subunit alpha Nav1.3 Antibody,SCN3A Antibody,KIAA1356 Antibody,NAC3 AntibodyMore alternative names for the antibody
brain III voltage-gated sodium channel antibody|NAC3 antibody|Nav1.3 antibody|SCN3A antibody|SCN3A_HUMAN antibody|Sodium channel protein brain III subunit alpha antibody|Sodium channel protein type 3 subunit alpha antibody|Sodium channel protein type III subunit alpha antibody|Sodium channel protein, brain III subunit alpha antibody|sodium channel, brain type III, alpha subunit antibody|sodium channel, neuronal type III, alpha subunit antibody|sodium channel, voltage-gated, type III, alpha polypeptide antibody|sodium channel, voltage-gated, type III, alpha subunit antibody|Voltage gated sodium channel subtype III antibody|Voltage gated sodium channel subunit alpha Nav1.3 antibody|Voltage-gated sodium channel subtype III antibody|Voltage-gated sodium channel subunit alpha Nav1.3 antibody
Anti-SCN3A antibody (ab65164)
Anti-SCN3A antibody (ab65164)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Sodium channel protein type 3 subunit alpha protein (274-400AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:6328( Human), Entrez Gene:20269( Mouse), Entrez Gene:497770( Rat), Omim:182391( Human), SwissProt:Q9NY46( Human), SwissProt:P08104( Rat), Unigene:435274( Human), Unigene:330256( Mouse), Unigene:87394( Rat)
|Protein function|| |
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
|Protein sequence and domain|| |
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.3/SCN3A subfamily. The sequence contains 4 internal repeats, each with 5 hydrophobic segments (S1,S2,S3,S5,S6) and one positively charged segment (S4). Segments S4 are probably the voltage-sensors and are characterized by a series of positively charged amino acids at every third position.
|Protein post-translational modifications|| |
May be ubiquitinated by NEDD4L; which would promote its endocytosis.; Phosphorylation at Ser-1501 by PKC in a highly conserved cytoplasmic loop slows inactivation of the sodium channel and reduces peak sodium currents. .
|Protein cellular localization|| |
Cell membrane ; Multi-pass membrane protein .
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CUSABIO BIOTECH CO.
|Product type|| |
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