Anti-SCN3A Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SCN3A Antibody (CSB-PA885761ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Sodium channel protein type 3 subunit alpha Antibody,Sodium channel protein brain III subunit alpha Antibody,Sodium channel protein type III subunit alpha Antibody,Voltage-gated sodium channel subtype III Antibody,Voltage-gated sodium channel subunit alpha Nav1.3 Antibody,SCN3A Antibody,KIAA1356 Antibody,NAC3 Antibody

More alternative names for the antibody
brain III voltage-gated sodium channel antibody|NAC3 antibody|Nav1.3 antibody|SCN3A antibody|SCN3A_HUMAN antibody|Sodium channel protein brain III subunit alpha antibody|Sodium channel protein type 3 subunit alpha antibody|Sodium channel protein type III subunit alpha antibody|Sodium channel protein, brain III subunit alpha antibody|sodium channel, brain type III, alpha subunit antibody|sodium channel, neuronal type III, alpha subunit antibody|sodium channel, voltage-gated, type III, alpha polypeptide antibody|sodium channel, voltage-gated, type III, alpha subunit antibody|Voltage gated sodium channel subtype III antibody|Voltage gated sodium channel subunit alpha Nav1.3 antibody|Voltage-gated sodium channel subtype III antibody|Voltage-gated sodium channel subunit alpha Nav1.3 antibody
Anti-SCN3A antibody (ab65164)
Close sc-517010|sc-28752|sc-22203|sc-22202|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SCN3A Antibody

Catalogue No.

CSB-PA885761ESR1HU

Reactivity

Human

Immunogen

Recombinant human Sodium channel protein type 3 subunit alpha protein (274-400AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

226 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:6328( Human), Entrez Gene:20269( Mouse), Entrez Gene:497770( Rat), Omim:182391( Human), SwissProt:Q9NY46( Human), SwissProt:P08104( Rat), Unigene:435274( Human), Unigene:330256( Mouse), Unigene:87394( Rat)

Protein function

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.

Protein sequence and domain

Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.3/SCN3A subfamily. The sequence contains 4 internal repeats, each with 5 hydrophobic segments (S1,S2,S3,S5,S6) and one positively charged segment (S4). Segments S4 are probably the voltage-sensors and are characterized by a series of positively charged amino acids at every third position.

Protein post-translational modifications

May be ubiquitinated by NEDD4L; which would promote its endocytosis.; Phosphorylation at Ser-1501 by PKC in a highly conserved cytoplasmic loop slows inactivation of the sodium channel and reduces peak sodium currents. .

Protein cellular localization

Cell membrane ; Multi-pass membrane protein .

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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