Anti-SCN7A Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SCN7A Antibody (CSB-PA2108ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Sodium channel protein type 7 subunit alpha Antibody,Putative voltage-gated sodium channel subunit alpha Nax Antibody,Sodium channel protein cardiac and skeletal muscle subunit alpha Antibody,Sodium channel protein type VII subunit alpha Antibody,SCN7A Antibody,SCN6A Antibody

More alternative names for the antibody
Putative voltage gated sodium channel subunit alpha Nax antibody|SCN 6A antibody|SCN 7A antibody|SCN6A antibody|Sodium channel protein cardiac and skeletal muscle subunit alpha antibody|Sodium channel protein type 7 subunit alpha antibody|Sodium channel protein type VII subunit alpha antibody|Sodium channel voltage gated type VI alpha polypeptide antibody|Sodium channel voltage gated type VII alpha antibody|Sodium channel voltage gated type VII alpha polypeptide antibody|Voltage dependent sodium channel alpha subunit antibody
Anti-SCN7A antibody (ab66499)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-SCN7A Antibody

Catalogue No.

CSB-PA2108ESR1HU

Reactivity

Human

Immunogen

Recombinant human Sodium channel protein type 7 subunit alpha protein (265-368AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

193 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:6332( Human), Entrez Gene:20272( Mouse), Entrez Gene:64155( Rat), Omim:182392( Human), SwissProt:Q01118( Human), SwissProt:Q62467( Mouse), SwissProt:P97706( Rat), Unigene:695947( Human)

Protein function

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. .

Protein tissue specificity

Heart and uterus. .

Protein sequence and domain

Belongs to the sodium channel (TC 1.A.1.10) family. SCN7A subfamily. The sequence contains 4 internal repeats, each with 5 hydrophobic segments (S1,S2,S3,S5,S6) and one positively charged segment (S4). Segments S4 are probably the voltage-sensors and are characterized by a series of positively charged amino acids at every third position.

Protein post-translational modifications

Lacks the cysteine which covalently binds the conotoxin GVIIJ. This cysteine (position 656) is speculated in other sodium channel subunits alpha to be implied in covalent binding with the sodium channel subunit beta-2 or beta-4. .

Protein cellular localization

Cell membrane ; Multi-pass membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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