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Rabbit Anti-SCYL1 Antibody (CSB-PA839356DSR1HU)
Supplier: CUSABIO BIOTECH CO.
N-terminal kinase-like protein Antibody,Coated vesicle-associated kinase of 90 kDa Antibody,SCY1-like protein 1 Antibody,Telomerase regulation-associated protein Antibody,Telomerase transcriptional element-interacting factor Antibody,Teratoma-associated tyrosine kinase Antibody,SCYL1 Antibody,CVAK90 Antibody,GKLP Antibody,NTKL Antibody,TAPK Antibody,TEIF Antibody,TRAP Antibody,HT019 AntibodyMore alternative names for the antibody
Coated vesicle associated kinase of 90 kDa antibody|Coated vesicle-associated kinase of 90 kDa antibody|CVAK90 antibody|GKLP antibody|HT019 antibody|Likely ortholog of mouse N terminal kinase like protein antibody|MGC78454 antibody|N terminal kinase like antibody|N terminal kinase like protein antibody|N-terminal kinase-like protein antibody|NKTL antibody|NTKL antibody|NTKL_HUMAN antibody|NTKLBP1 antibody|P105 antibody|SCY L1 antibody|SCY1 like 1 antibody|SCY1 like 1 protein 1 antibody|SCY1-like protein 1 antibody|SCYL 1 antibody|Scyl1 antibody|SCYL1BP1 antibody|TAPK antibody|TEIF antibody|Telomerase regulation associated protein antibody|Telomerase regulation-associated protein antibody|Telomerase transcriptional element interacting factor antibody|Telomerase transcriptional element-interacting factor antibody|Teratoma associated tyrosine kinase antibody|Teratoma-associated tyrosine kinase antibody|TRAP antibody
Anti-SCYL1 antibody (ab76851)
Anti-SCYL1 antibody (ab76851)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human N-terminal kinase-like protein (460-740AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:57410( Human), Entrez Gene:78891( Mouse), Entrez Gene:293684( Rat), Omim:607982( Human), SwissProt:Q96KG9( Human), SwissProt:Q9EQC5( Mouse), SwissProt:Q5M9F8( Rat), Unigene:238839( Human), Unigene:276063( Mouse), Unigene:143751( Rat)
|Protein function|| |
Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). Involved in the maintenance of the Golgi apparatus morphology (PubMed:26581903). Has no detectable kinase activity in vitro (PubMed:18556652). .; Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region. .
|Protein tissue specificity|| |
|Involvement in disease|| |
Spinocerebellar ataxia, autosomal recessive, 21 (SCAR21) [MIM:616719]: A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR21 is characterized by cerebellar atrophy and ataxia with onset in early childhood. Patients also manifest recurrent episodes of liver failure, hepatic fibrosis and a peripheral neuropathy. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the protein kinase superfamily. The protein kinase domain is predicted to be catalytically inactive.
|Protein cellular localization|| |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Endoplasmic reticulum-Golgi intermediate compartment . Golgi apparatus, cis-Golgi network . Note=Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner.; Isoform 1: Cytoplasm. Note=Cytoplasmic throughout the cell cycle.; Isoform 2: Cytoplasm. Note=Cytoplasmic throughout the cell cycle.; Isoform 3: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic during interphase and centrosomal during mitosis, it localizes to the centrosomes in a microtubule-independent manner.; Isoform 6: Nucleus .
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CUSABIO BIOTECH CO.
|Product type|| |
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