Anti-SERPINA3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SERPINA3 Antibody (CSB-PA021059ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

ACT Antibody,Cell growth-inhibiting gene 24/25 protein Antibody,Serpin A3 Antibody,SERPINA3 Antibody,AACT Antibody,GIG24 Antibody, GIG25 Antibody

More alternative names for the antibody
SERPINA3 antibody|AACT antibody|AACT_HUMAN antibody|ACT antibody|Alpha-1-antichymotrypsin His-Pro-less antibody|Antichymotrypsin antibody|Cell growth inhibiting gene 24/25 protein antibody|Cell growth-inhibiting gene 24/25 protein antibody|GIG24 antibody|GIG25 antibody|Growth inhibiting protein 24 antibody|Growth inhibiting protein 25 antibody|MGC88254 antibody|Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase, antitrypsin) member 3 antibody|Serine (or cysteine) proteinase inhibitor clade A member 3 antibody|Serine proteinase inhibitor clade A member 3 antibody|Serpin A3 antibody|Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3 antibody|SERPINA3 antibody
Anti-alpha 1 Antichymotrypsin antibody [EPR17088-68] (ab205198)
Close sc-69983|sc-69982|sc-59430|sc-59432|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SERPINA3 Antibody

Catalogue No.

CSB-PA021059ESR1HU

Reactivity

Human

Immunogen

Recombinant human Alpha-1-antichymotrypsin protein (24-423AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

47 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:12( Human), Omim:107280 ( Human), SwissProt:P01011( Human), Unigene:534293( Human), Unigene:710488( Human)

Protein function

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. .

Protein tissue specificity

Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains. .

Protein sequence and domain

Belongs to the serpin family. The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable.

Protein post-translational modifications

N- and O-glycosylated. .

Protein cellular localization

Secreted.

Research area

All research areas>Signaling Intermediates>AACT
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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