Anti-SERPINA6 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SERPINA6 Antibody (CSB-PA021062ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

CBG Antibody,Serpin A6 Antibody,Transcortin Antibody,SERPINA6 Antibody,CBG Antibody

More alternative names for the antibody
CBG antibody|CBG_HUMAN antibody|corticosteroid binding globulin antibody|Corticosteroid-binding globulin antibody|serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6 antibody|Serpin A6 antibody|serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6 antibody|Serpina6 antibody|Transcortin antibody
Anti-Cortisol Binding Globulin antibody (ab107368)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SERPINA6 Antibody

Catalogue No.

CSB-PA021062ESR2HU

Reactivity

Human

Immunogen

Recombinant human Corticosteroid-binding globulin protein (136-405AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

45 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:866( Human), Entrez Gene:12401( Mouse), Omim:122500( Human), SwissProt:P08185( Human), SwissProt:Q06770( Mouse), Unigene:532635( Human), Unigene:290079( Mouse)

Protein function

Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. .

Protein tissue specificity

Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.

Involvement in disease

Corticosteroid-binding globulin deficiency (CBG deficiency) [MIM:611489]: Extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the serpin family. Proteolytic cleavage leads to an important conformation change. This reduces the affinity for steroids.

Protein post-translational modifications

N-glycosylated; binds 5 oligosaccharide chains.; Glycosylation in position Asn-260 is needed for steroid binding.

Protein cellular localization

Secreted.

Research area

All research areas>Synthesis and Degradation>CBG
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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