Anti-SERPINB6 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SERPINB6 Antibody (CSB-PA021074ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Serpin B6 Antibody,Cytoplasmic antiproteinase Antibody,CAP Antibody,Peptidase inhibitor 6 Antibody,PI-6 Antibody,Placental thrombin inhibitor Antibody,SERPINB6 Antibody,PI6 Antibody,PTI Antibody

More alternative names for the antibody
CAP antibody|Cytoplasmic antiproteinase antibody|Peptidase inhibitor 6 antibody|PI-6 antibody|PI6 antibody|Placental thrombin inhibitor antibody|Protease inhibitor 6 (placental thrombin inhibitor) antibody|PTI antibody|Serpin B6 antibody|SERPINB6 antibody|SPB6_HUMAN antibody
Anti-SerpinB6 antibody [2F8] (ab119393)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-SERPINB6 Antibody

Catalogue No.

CSB-PA021074ESR2HU

Reactivity

Human

Immunogen

Recombinant human Serpin B6 protein (180-300AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

42 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5269( Human), Omim:173321( Human), SwissProt:P35237( Human), Unigene:519523( Human)

Protein function

May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. .

Protein tissue specificity

Expressed in keratinocytes (at protein level). Highest levels in skeletal muscle. Also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. Expressed in the inner ear hair cells. Expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions. .

Involvement in disease

Deafness, autosomal recessive, 91 (DFNB91) [MIM:613453]: A form of non-syndromic deafness characterized by progressive and age-dependent sensorineural hearing loss. Vestibular function is normal. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the serpin family. Ov-serpin subfamily.

Protein cellular localization

Cytoplasm .

Research area

All research areas>Signaling Intermediates>Serpin
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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