Anti-SERPIND1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SERPIND1 Antibody (CSB-PA021080ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Heparin cofactor 2 Antibody,Heparin cofactor II Antibody,HC-II Antibody,Protease inhibitor leuserpin-2 Antibody,HLS2 Antibody,Serpin D1 Antibody,SERPIND1 Antibody,HCF2 Antibody

More alternative names for the antibody
D22S673 antibody|HC II antibody|HC-II antibody|HC2 antibody|HCF2 antibody|HEP2_HUMAN antibody|Heparin cofactor 2 antibody|Heparin cofactor II antibody|HLS2 antibody|Leuserpin 2 antibody|LS2 antibody|Protease inhibitor leuserpin 2 antibody|Protease inhibitor leuserpin-2 antibody|serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 antibody|Serpin D1 antibody|serpin peptidase inhibitor, clade D (heparin cofactor), member 1 antibody|SERPIND1 antibody|THPH10 antibody
Anti-Heparin Cofactor II antibody [74E5] (ab51051)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SERPIND1 Antibody

Catalogue No.

CSB-PA021080ESR1HU

Reactivity

Human

Immunogen

Recombinant human Heparin cofactor 2 protein (20-290AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

57 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:3053( Human), Omim:142360( Human), SwissProt:P05546( Human), Unigene:474270( Human)

Protein function

Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. .; Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils. .

Protein tissue specificity

Expressed predominantly in liver. Also present in plasma.

Involvement in disease

Thrombophilia due to heparin cofactor 2 deficiency (THPH10) [MIM:612356]: A hemostatic disorder characterized by a tendency to recurrent thrombosis. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the serpin family. The N-terminal acidic repeat region mediates, in part, the glycosaminoglycan-accelerated thrombin inhibition.

Protein post-translational modifications

Phosphorylated by FAM20C in the extracellular medium. .

Research area

All research areas>Signaling Intermediates>HCII
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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