Anti-SESN3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SESN3 Antibody (CSB-PA021097ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

SESN3;SEST3 Antibody

More alternative names for the antibody
MGC29667 antibody|OTTHUMP00000236979 antibody|OTTHUMP00000236986 antibody|SESN3 antibody|SESN3_HUMAN antibody|SEST3 antibody|Sestrin 3 antibody|Sestrin-3 antibody
Anti-SESN3 antibody (ab97792)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SESN3 Antibody

Catalogue No.

CSB-PA021097ESR2HU

Reactivity

Human

Immunogen

Recombinant human Sestrin-3 protein (1-310AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

57 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:143686( Human), Entrez Gene:75747( Mouse), Entrez Gene:315427( Rat), Omim:607768( Human), SwissProt:P58005( Human), SwissProt:Q9CYP7( Mouse), Unigene:659934( Human), Unigene:325126( Mouse), Unigene:439776( Mouse)

Protein function

May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity). .

Protein tissue specificity

Widely expressed. .

Protein sequence and domain

Belongs to the sestrin family. The C-terminal domain may mediate interaction with GATOR2 and regulation of TORC1 signaling.

Protein cellular localization

Cytoplasm .

Research area

All research areas>Tumor Suppressor/Apoptosis>SESN
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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