Anti-SHC4 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SHC4 Antibody (CSB-PA747568ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Rai-like protein Antibody,RaLP Antibody,SHC-transforming protein D Antibody, hShcD Antibody,Src homology 2 domain-containing-transforming protein C4 Antibody,SH2 domain protein C4 Antibody

More alternative names for the antibody
hShcD antibody|MGC34023 antibody|Rai like protein antibody|Rai-like protein antibody|RaLP antibody|SH2 domain protein C4 antibody|SHC (Src homology 2 domain containing) family member 4 antibody|SHC 4 antibody|SHC antibody|SHC family member 4 antibody|SHC transforming protein 4 antibody|SHC transforming protein D antibody|SHC-transforming protein 4 antibody|SHC-transforming protein D antibody|Shc4 antibody|SHC4_HUMAN antibody|SHCD antibody|Src homology 2 domain containing family member 4 antibody|Src homology 2 domain containing transforming protein C4 antibody|Src homology 2 domain-containing-transforming protein C4 antibody
Anti-SHC4 antibody – N-terminal (ab174908)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SHC4 Antibody

Catalogue No.

CSB-PA747568ESR1HU

Reactivity

Human

Immunogen

Recombinant human SHC-transforming protein 4 protein (1-185AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

68 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:399694( Human), SwissProt:Q6S5L8( Human), Unigene:642615( Human)

Protein function

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1. .

Protein tissue specificity

Only expressed in melanomas. Weakly expressed in normal melanocytes and benign nevi. Highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumor cells acquire migratory competence and invasive potential. .

Protein post-translational modifications

Phosphorylated; the phosphorylation is enhanced by EGF. Phosphorylation at Tyr-424 is required for the interaction with GRB2. .

Protein cellular localization

Cell junction, synapse, postsynaptic cell membrane. Note=Colocalized with MUSK at the neuromuscular junction. .

Research area

All research areas>Signaling Intermediates>Shc
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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