Anti-SIGIRR Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SIGIRR Antibody (CSB-PA743558ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Single Ig IL-1-related receptor Antibody,Single Ig IL-1R-related molecule Antibody,Single immunoglobulin domain-containing IL1R-related protein Antibody,Toll/interleukin-1 receptor 8 Antibody,TIR8 Antibody,SIGIRR Antibody,UNQ301/PRO342 Antibody

More alternative names for the antibody
TIR 8 antibody|TIR8 antibody|Toll/interleukin 1 receptor 8 antibody|Toll/interleukin-1 receptor 8 antibody
Anti-SIGIRR antibody (ab22053)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-SIGIRR Antibody

Catalogue No.

CSB-PA743558ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Single Ig IL-1-related receptor protein (1-120AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

45 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:59307( Human), Entrez Gene:24058( Mouse), Omim:605478( Human), SwissProt:Q6IA17( Human), SwissProt:Q9JLZ8( Mouse), Unigene:501624( Human), Unigene:38017( Mouse)

Protein function

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. .

Protein tissue specificity

Mainly expressed in epithelial tissues such as kidney, lung and gut. .

Protein sequence and domain

Belongs to the interleukin-1 receptor family.

Protein cellular localization

Membrane ; Single-pass type III membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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