Anti-SLC12A6 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SLC12A6 Antibody (CSB-PA887049DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Solute carrier family 12 member 6 Antibody,Electroneutral potassium-chloride cotransporter 3 Antibody,K-Cl cotransporter 3 Antibody,SLC12A6 Antibody,KCC3 Antibody

More alternative names for the antibody
ACCPN antibody|Electroneutral potassium-chloride cotransporter 3 antibody|Furosemide sensitive KCl cotransporter 3 antibody|Gaxp antibody|K-Cl cotransporter 3 antibody|KCC 3 antibody|KCC 3A antibody|KCC 3B antibody|KCC3 A antibody|KCC3 antibody|KCC3 B antibody|KCC3A antibody|KCC3B antibody|Potassium chloride cotransporter 3 antibody|Potassium chloride cotransporter KCC3a S3 antibody|S12A6_HUMAN antibody|SLC12 A6 antibody|SLC12A 6 antibody|SLC12A6 antibody|Solute carrier family 12 (potassium/chloride transporters), member 6 antibody|Solute carrier family 12 member 6 antibody|Solute carrier family 12, member 6 antibody
Anti-SLC12A6 antibody – C-terminal (ab191451)
Close sc-19424|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SLC12A6 Antibody

Catalogue No.

CSB-PA887049DSR2HU

Reactivity

Human

Immunogen

Recombinant human Solute carrier family 12 member 6 protein (60-190AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

127 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9990( Human), Entrez Gene:107723( Mouse), Entrez Gene:691209( Rat), Omim:604878( Human), SwissProt:Q9UHW9( Human), SwissProt:Q924N4( Mouse), Unigene:510939( Human), Unigene:491155( Mouse), Unigene:13442( Rat)

Protein function

Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.

Protein tissue specificity

Highly expressed in heart, brain and kidney. Detected at lower levels in skeletal muscle, placenta, lung and pancreas. Detected in umbilical vein endothelial cells. Isoform 2 is more abundant in kidney. Isoform 5 is testis specific. Expressed in the proximal tubule of the kidney (at protein level). .

Involvement in disease

Agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) [MIM:218000]: A disease that is characterized by severe progressive sensorimotor neuropathy, mental retardation, dysmorphic features and complete or partial agenesis of the corpus callosum. Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the SLC12A transporter family.

Protein post-translational modifications

N-glycosylated. .

Protein cellular localization

Basolateral cell membrane ; Multi-pass membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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