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Rabbit Anti-SLC24A1 Antibody (CSB-PA021469ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Sodium/potassium/calcium exchanger 1 Antibody,Na(+)/K(+)/Ca(2+)-exchange protein 1 Antibody,Retinal rod Na-Ca+K exchanger Antibody,Solute carrier family 24 member 1 Antibody,SLC24A1 Antibody,KIAA0702 Antibody,NCKX1 AntibodyMore alternative names for the antibody
CSNB1D antibody|HsT17412 antibody|KIAA0702 antibody|Na(+)/K(+)/Ca(2+) exchange protein 1 antibody|Na(+)/K(+)/Ca(2+)-exchange protein 1 antibody|NCKX antibody|NCKX1 antibody|NCKX1_HUMAN antibody|Retinal rod Na Ca+K exchanger antibody|Retinal rod Na+/Ca+/K+ exchanger antibody|Retinal rod Na-Ca+K exchanger antibody|RODX antibody|Slc24a1 antibody|Sodium/potassium/calcium exchanger 1 antibody|Solute carrier family 24 (sodium/potassium/calcium exchanger) member 1 antibody|Solute carrier family 24 member 1 antibody
Anti-SLC24A1 antibody (ab209069)
Anti-SLC24A1 antibody (ab209069)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Sodium/potassium/calcium exchanger 1 protein (330-452AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9187" target="_blank">Entrez Gene:9187( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=214111" target="_blank">Entrez Gene:214111( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/603617" target="_blank">Omim:603617( Human)</a>, <a href="http://www.uniprot.org/uniprot/O60721" target="_blank">SwissProt:O60721( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=173092" target="_blank">Unigene:173092( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=156124" target="_blank">Unigene:156124( Mouse)</a>
|Protein function|| |
Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). .
|Protein tissue specificity|| |
Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer. .
|Involvement in disease|| |
Night blindness, congenital stationary, 1D (CSNB1D) [MIM:613830]: An autosomal recessive form of congenital stationary night blindness, a non-progressive retinal disorder characterized by impaired night vision. CSNB1D is characterized by a Riggs type of electroretinogram (proportionally reduced a- and b-waves). Patients have visual acuity within the normal range and no symptoms of myopia and/or nystagmus. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
|Protein post-translational modifications|| |
The uncleaved signal sequence is required for efficient membrane targeting and proper membrane integration.
|Protein cellular localization|| |
Membrane; Multi-pass membrane protein.
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|Product type|| |
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