Anti-SLC24A1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SLC24A1 Antibody (CSB-PA021469ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Sodium/potassium/calcium exchanger 1 Antibody,Na(+)/K(+)/Ca(2+)-exchange protein 1 Antibody,Retinal rod Na-Ca+K exchanger Antibody,Solute carrier family 24 member 1 Antibody,SLC24A1 Antibody,KIAA0702 Antibody,NCKX1 Antibody

More alternative names for the antibody
CSNB1D antibody|HsT17412 antibody|KIAA0702 antibody|Na(+)/K(+)/Ca(2+) exchange protein 1 antibody|Na(+)/K(+)/Ca(2+)-exchange protein 1 antibody|NCKX antibody|NCKX1 antibody|NCKX1_HUMAN antibody|Retinal rod Na Ca+K exchanger antibody|Retinal rod Na+/Ca+/K+ exchanger antibody|Retinal rod Na-Ca+K exchanger antibody|RODX antibody|Slc24a1 antibody|Sodium/potassium/calcium exchanger 1 antibody|Solute carrier family 24 (sodium/potassium/calcium exchanger) member 1 antibody|Solute carrier family 24 member 1 antibody
Anti-SLC24A1 antibody (ab209069)
Close sc-393400|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SLC24A1 Antibody

Catalogue No.

CSB-PA021469ESR1HU

Reactivity

Human

Immunogen

Recombinant human Sodium/potassium/calcium exchanger 1 protein (330-452AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

121 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9187( Human), Entrez Gene:214111( Mouse), Omim:603617( Human), SwissProt:O60721( Human), Unigene:173092( Human), Unigene:156124( Mouse)

Protein function

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). .

Protein tissue specificity

Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer. .

Involvement in disease

Night blindness, congenital stationary, 1D (CSNB1D) [MIM:613830]: An autosomal recessive form of congenital stationary night blindness, a non-progressive retinal disorder characterized by impaired night vision. CSNB1D is characterized by a Riggs type of electroretinogram (proportionally reduced a- and b-waves). Patients have visual acuity within the normal range and no symptoms of myopia and/or nystagmus. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.

Protein post-translational modifications

The uncleaved signal sequence is required for efficient membrane targeting and proper membrane integration.

Protein cellular localization

Membrane; Multi-pass membrane protein.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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