Anti-SLC2A1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SLC2A1 Antibody (CSB-PA021546ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Glucose transporter type 1 Antibody, erythrocyte/brain Antibody, GLUT-1 Antibody,HepG2 glucose transporter Antibody,SLC2A1 Antibody,GLUT1 Antibody

More alternative names for the antibody
Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity) antibody|CSE antibody|DYT17 antibody|DYT18 antibody|DYT9 antibody|EIG12 antibody|erythrocyte/brain antibody|Erythrocyte/hepatoma glucose transporter antibody|facilitated glucose transporter member 1 antibody|Glucose transporter 1 antibody|Glucose transporter type 1 antibody|Glucose transporter type 1, erythrocyte/brain antibody|GLUT antibody|GLUT-1 antibody|GLUT1 antibody|GLUT1DS antibody|GLUTB antibody|GT1 antibody|GTG1 antibody|Gtg3 antibody|GTR1_HUMAN antibody|HepG2 glucose transporter antibody|HTLVR antibody|Human T cell leukemia virus (I and II) receptor antibody|MGC141895 antibody|MGC141896 antibody|PED antibody|RATGTG1 antibody|Receptor for HTLV 1 and HTLV 2 antibody|SLC2A1 antibody|Solute carrier family 2 (facilitated glucose transporter), member 1 antibody|Solute carrier family 2 antibody|Solute carrier family 2, facilitated glucose transporter member 1 antibody
Anti-Glucose Transporter GLUT1 antibody [SPM498] (ab40084)
Close sc-377228|sc-1605|sc-7903|sc-1603|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SLC2A1 Antibody

Catalogue No.

CSB-PA021546ESR2HU

Reactivity

Human

Immunogen

Recombinant human Solute carrier family 2, facilitated glucose transporter member 1 protein (210-310AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

54 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:6513( Human), Entrez Gene:20525( Mouse), Entrez Gene:24778( Rat), Omim:138140( Human), SwissProt:P11166( Human), SwissProt:P17809( Mouse), SwissProt:P11167( Rat), Unigene:473721( Human), Unigene:721551( Human), Unigene:21002( Mouse), Unigene:3205( Rat)

Protein function

Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. .

Protein tissue specificity

Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues. .

Involvement in disease

GLUT1 deficiency syndrome 1 (GLUT1DS1) [MIM:606777]: A neurologic disorder showing wide phenotypic variability. The most severe ‘classic’ phenotype comprises infantile-onset epileptic encephalopathy associated with delayed development, acquired microcephaly, motor incoordination, and spasticity. Onset of seizures, usually characterized by apneic episodes, staring spells, and episodic eye movements, occurs within the first 4 months of life. Other paroxysmal findings include intermittent ataxia, confusion, lethargy, sleep disturbance, and headache. Varying degrees of cognitive impairment can occur, ranging from learning disabilities to severe mental retardation. . Note=The disease is caused by mutations affecting the gene represented in this entry.; GLUT1 deficiency syndrome 2 (GLUT1DS2) [MIM:612126]: A clinically variable disorder characterized primarily by onset in childhood of paroxysmal exercise-induced dyskinesia. The dyskinesia involves transient abnormal involuntary movements, such as dystonia and choreoathetosis, induced by exercise or exertion, and affecting the exercised limbs. Some patients may also have epilepsy, most commonly childhood absence epilepsy. Mild mental retardation may also occur. In some patients involuntary exertion-induced dystonic, choreoathetotic, and ballistic movements may be associated with macrocytic hemolytic anemia. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Epilepsy, idiopathic generalized 12 (EIG12) [MIM:614847]: A disorder characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain. Seizure types include juvenile myoclonic seizures, absence seizures, and generalized tonic-clonic seizures. In some EIG12 patients seizures may remit with age. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.; Dystonia 9 (DYT9) [MIM:601042]: An autosomal dominant neurologic disorder characterized by childhood onset of paroxysmal choreoathetosis and progressive spastic paraplegia. Most patients show some degree of cognitive impairment. Other variable features may include seizures, migraine headaches, and ataxia. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Stomatin-deficient cryohydrocytosis with neurologic defects (SDCHCN) [MIM:608885]: A rare form of stomatocytosis characterized by episodic hemolytic anemia, cold-induced red cells cation leak, erratic hyperkalemia, neonatal hyperbilirubinemia, hepatosplenomegaly, cataracts, seizures, mental retardation, and movement disorder. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Protein cellular localization

Cell membrane; Multi-pass membrane protein. Melanosome. Note=Localizes primarily at the cell surface. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Research area

All research areas>Transport and Trafficking>Glut
(View all antibody categories related to Transport and Trafficking)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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