Anti-SMAD9 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SMAD9 Antibody (CSB-PA021794ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

MAD homolog 9 Antibody,Mothers against DPP homolog 9 Antibody,Madh6 Antibody,SMAD family member 9 Antibody,SMAD 9 Antibody,SMAD9 Antibody,MADH6 Antibody, MADH9 Antibody

More alternative names for the antibody
MAD homolog 9 antibody|Madh6 antibody|Mothers against decapentaplegic antibody|Mothers against decapentaplegic homolog 9 antibody|Mothers against DPP homolog 9 antibody|SMAD 9 antibody|SMAD family member 9 antibody|SMAD, mothers against DPP homolog 9 (Drosophila) antibody|SMAD8A antibody|SMAD8B antibody|Smad9 antibody|SMAD9_HUMAN antibody
Anti-SMAD9 antibody (ab115900)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SMAD9 Antibody

Catalogue No.

CSB-PA021794ESR2HU

Reactivity

Human

Immunogen

Recombinant human Mothers against decapentaplegic homolog 9 protein (1-300AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

52 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:4093( Human), Entrez Gene:55994( Mouse), Entrez Gene:85435( Rat), Omim:603295( Human), SwissProt:O15198( Human), SwissProt:Q9JIW5( Mouse), SwissProt:O54835( Rat), Unigene:123119( Human), Unigene:244353( Mouse), Unigene:10862( Rat)

Protein function

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).

Protein tissue specificity

Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney.

Involvement in disease

Pulmonary hypertension, primary, 2 (PPH2) [MIM:615342]: A rare disorder characterized by plexiform lesions of proliferating endothelial cells in pulmonary arterioles. The lesions lead to elevated pulmonary arterial pression, right ventricular failure, and death. The disease can occur from infancy throughout life and it has a mean age at onset of 36 years. Penetrance is reduced. Although familial pulmonary hypertension is rare, cases secondary to known etiologies are more common and include those associated with the appetite-suppressant drugs. . Note=The disease may be caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the dwarfin/SMAD family.

Protein post-translational modifications

Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.

Protein cellular localization

Cytoplasm . Nucleus . Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity). .

Research area

All research areas>Transcription Regulators>Smad
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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