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Rabbit Anti-SMAD9 Antibody (CSB-PA021794ESR2HU)
Supplier: CUSABIO BIOTECH CO.
MAD homolog 9 Antibody,Mothers against DPP homolog 9 Antibody,Madh6 Antibody,SMAD family member 9 Antibody,SMAD 9 Antibody,SMAD9 Antibody,MADH6 Antibody, MADH9 AntibodyMore alternative names for the antibody
MAD homolog 9 antibody|Madh6 antibody|Mothers against decapentaplegic antibody|Mothers against decapentaplegic homolog 9 antibody|Mothers against DPP homolog 9 antibody|SMAD 9 antibody|SMAD family member 9 antibody|SMAD, mothers against DPP homolog 9 (Drosophila) antibody|SMAD8A antibody|SMAD8B antibody|Smad9 antibody|SMAD9_HUMAN antibody
Anti-SMAD9 antibody (ab115900)
Anti-SMAD9 antibody (ab115900)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Mothers against decapentaplegic homolog 9 protein (1-300AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:4093( Human), Entrez Gene:55994( Mouse), Entrez Gene:85435( Rat), Omim:603295( Human), SwissProt:O15198( Human), SwissProt:Q9JIW5( Mouse), SwissProt:O54835( Rat), Unigene:123119( Human), Unigene:244353( Mouse), Unigene:10862( Rat)
|Protein function|| |
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).
|Protein tissue specificity|| |
Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney.
|Involvement in disease|| |
Pulmonary hypertension, primary, 2 (PPH2) [MIM:615342]: A rare disorder characterized by plexiform lesions of proliferating endothelial cells in pulmonary arterioles. The lesions lead to elevated pulmonary arterial pression, right ventricular failure, and death. The disease can occur from infancy throughout life and it has a mean age at onset of 36 years. Penetrance is reduced. Although familial pulmonary hypertension is rare, cases secondary to known etiologies are more common and include those associated with the appetite-suppressant drugs. . Note=The disease may be caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the dwarfin/SMAD family.
|Protein post-translational modifications|| |
Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.
|Protein cellular localization|| |
Cytoplasm . Nucleus . Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity). .
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CUSABIO BIOTECH CO.
|Product type|| |
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