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Rabbit Anti-SMARCC1 Antibody (CSB-PA821715ESR2HU)
Supplier: CUSABIO BIOTECH CO.
BRG1-associated factor 155 Antibody,BAF155 Antibody,SWI/SNF complex 155 kDa subunit Antibody,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 Antibody,SMARCC1 Antibody,BAF155 AntibodyMore alternative names for the antibody
AI115498 antibody|SWI3 antibody
Anti-SMARCC1 antibody (ab126180)
Anti-SMARCC1 antibody (ab126180)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human SWI/SNF complex subunit SMARCC1 protein (80-320AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:6599( Human), Entrez Gene:20588( Mouse), Entrez Gene:301020( Rat), Omim:601732( Human), SwissProt:Q92922( Human), SwissProt:P97496( Mouse), Unigene:476179( Human), Unigene:85410( Mouse), Unigene:94211( Rat)
|Protein function|| |
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). .
|Protein tissue specificity|| |
Expressed in brain, heart, muscle, placenta, lung, liver, muscle, kidney and pancreas.
|Protein sequence and domain|| |
Belongs to the SMARCC family.
|Protein post-translational modifications|| |
Phosphorylated on undefined residues at the G2/M transition by ERK1 and other kinases. This may contribute to cell cycle specific inactivation of remodeling complexes containing the phosphorylated protein. .
|Protein cellular localization|| |
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|Product type|| |
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