Anti-SMARCC1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SMARCC1 Antibody (CSB-PA821715ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

BRG1-associated factor 155 Antibody,BAF155 Antibody,SWI/SNF complex 155 kDa subunit Antibody,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 Antibody,SMARCC1 Antibody,BAF155 Antibody

More alternative names for the antibody
AI115498 antibody|SWI3 antibody
Anti-SMARCC1 antibody (ab126180)
Close sc-32763|sc-48350|sc-137138|sc-365505|sc-365543|sc-10756|sc-9748|sc-9746|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SMARCC1 Antibody

Catalogue No.

CSB-PA821715ESR2HU

Reactivity

Human

Immunogen

Recombinant human SWI/SNF complex subunit SMARCC1 protein (80-320AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

122 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:6599( Human), Entrez Gene:20588( Mouse), Entrez Gene:301020( Rat), Omim:601732( Human), SwissProt:Q92922( Human), SwissProt:P97496( Mouse), Unigene:476179( Human), Unigene:85410( Mouse), Unigene:94211( Rat)

Protein function

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). .

Protein tissue specificity

Expressed in brain, heart, muscle, placenta, lung, liver, muscle, kidney and pancreas.

Protein sequence and domain

Belongs to the SMARCC family.

Protein post-translational modifications

Phosphorylated on undefined residues at the G2/M transition by ERK1 and other kinases. This may contribute to cell cycle specific inactivation of remodeling complexes containing the phosphorylated protein. .

Protein cellular localization

Nucleus.

Research area

All research areas>Transcription Regulators>BAF
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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