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Rabbit Anti-SNAP25 Antibody (CSB-PA021873ESR2HU)
Supplier: CUSABIO BIOTECH CO.
SNAP-25 Antibody,Super protein Antibody,SUP Antibody,Synaptosomal-associated 25 kDa protein Antibody,SNAP25 Antibody,SNAP AntibodyMore alternative names for the antibody
bA416N4.2 antibody|Bdr antibody|CMS18 antibody|dJ1068F16.2 antibody|FLJ23079 antibody|HGNC:11132 antibody|MGC105414 antibody|MGC139754 antibody|Resistance to inhibitors of cholinesterase 4 homolog antibody|RIC 4 antibody|RIC4 antibody|SEC 9 antibody|SEC9 antibody|SNAP 25 antibody|SNAP antibody|SNAP-25 antibody|SNAP-25B antibody|SNAP25 antibody|SNP 25 antibody|SNP25 antibody|SNP25_HUMAN antibody|sp antibody|SUP antibody|Super protein antibody|Synaptosomal associated 25 kDa protein antibody|Synaptosomal associated protein antibody|Synaptosomal associated protein 25 antibody|Synaptosomal associated protein 25kDa antibody|Synaptosomal-associated 25 kDa protein antibody|Synaptosomal-associated protein 25 antibody|Synaptosomal-associated protein, 25-KD antibody
Anti-SNAP25 antibody (ab5666)
Anti-SNAP25 antibody (ab5666)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Synaptosomal-associated protein 25 protein (1-206AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:6616( Human), Entrez Gene:20614( Mouse), Entrez Gene:25012( Rat), Entrez Gene:30712( Zebrafish), Omim:600322( Human), SwissProt:P60878( Chicken), SwissProt:Q5R1X1( Chimpanzee), SwissProt:Q17QQ3( Cow), SwissProt:P36978( Goldfish), SwissProt:P60880( Human), SwissProt:P60879( Mouse), SwissProt:P60881( Rat), SwissProt:P60877( Rhesus monkey), SwissProt:Q5TZ66( Zebrafish), SwissProt:Q6PC54( Zebrafish), Unigene:167317( Human), Unigene:45953( Mouse), Unigene:107689( Rat)
|Protein function|| |
t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. .
|Protein tissue specificity|| |
Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
|Involvement in disease|| |
Myasthenic syndrome, congenital, 18 (CMS18) [MIM:616330]: A form of congenital myasthenic syndrome, a group of disorders characterized by failure of neuromuscular transmission, including pre-synaptic, synaptic, and post-synaptic disorders that are not of autoimmune origin. Clinical features are easy fatigability and muscle weakness affecting the axial and limb muscles (with hypotonia in early-onset forms), the ocular muscles (leading to ptosis and ophthalmoplegia), and the facial and bulbar musculature (affecting sucking and swallowing, and leading to dysphonia). The symptoms fluctuate and worsen with physical effort. CMS18 is an autosomal dominant presynaptic disorder clinically characterized by early-onset muscle weakness and easy fatigability associated with delayed psychomotor development and ataxia. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the SNAP-25 family.
|Protein post-translational modifications|| |
Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association (By similarity). .
|Protein cellular localization|| |
Cytoplasm, perinuclear region . Cell membrane ; Lipid-anchor. Cell junction, synapse, synaptosome. Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity). .
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CUSABIO BIOTECH CO.
|Product type|| |
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