Anti-SOCS2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SOCS2 Antibody (CSB-PA022389ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

SOCS-2 Antibody,Cytokine-inducible SH2 protein 2 Antibody,CIS-2 Antibody,STAT-induced STAT inhibitor 2 Antibody,SSI-2 Antibody,SOCS2 Antibody,CIS2 Antibody, SSI2 Antibody, STATI2 Antibody

More alternative names for the antibody
CIS 2 antibody|CIS-2 antibody|CIS2 antibody|Cish 2 antibody|Cish2 antibody|Cytokine inducible SH2 protein 2 antibody|Cytokine-inducible SH2 protein 2 antibody|SOCS 2 antibody|SOCS-2 antibody|Socs2 antibody|SOCS2_HUMAN antibody|SSI 2 antibody|SSI-2 antibody|SSI2 antibody|STAT induced STAT inhibitor 2 antibody|STAT-induced STAT inhibitor 2 antibody|STATI 2 antibody|STATI2 antibody|Suppressor of cytokine signaling 2 antibody
Anti-SOCS2 antibody (ab3692)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SOCS2 Antibody

Catalogue No.

CSB-PA022389ESR2HU

Reactivity

Human

Immunogen

Recombinant human Suppressor of cytokine signaling 2 protein (1-198AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

22 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8835( Human), Entrez Gene:216233( Mouse), Entrez Gene:84607( Rat), Omim:605117( Human), SwissProt:O14508( Human), SwissProt:O35717( Mouse), SwissProt:O88582( Rat), Unigene:485572( Human), Unigene:474283( Mouse), Unigene:205056( Rat)

Protein function

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein tissue specificity

High expression in heart, placenta, lung, kidney and prostate.

Protein sequence and domain

The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.

Research area

All research areas>Signaling Intermediates>SOCS
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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