Anti-SRGN Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SRGN Antibody (CSB-PA022664ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Hematopoietic proteoglycan core protein Antibody,Platelet proteoglycan core protein Antibody,Secretory granule proteoglycan core protein Antibody,SRGN Antibody,PRG Antibody,PRG1 Antibody

More alternative names for the antibody
Chondroitin sulfate proteoglycan core protein antibody|Cytolytic granule proteoglycan core protein antibody|FLJ12930 antibody|gp600 antibody|Hematopoetic proteoglycan core protein antibody|Mastocytoma proteoglycan core protein antibody|MGC9289 antibody|OTTHUMP00000019716 antibody|P.PG antibody|PG19 core protein antibody|Pgsg antibody|Platelet proteoglycan core protein antibody|platelet proteoglycan protein core antibody|PLATELET PROTEOGLYCAN PROTEIN CORE; PPG antibody|PPG antibody|PRG antibody|PRG1 antibody|PROTEOGLYCAN 1 antibody|proteoglycan 1, secretory granule antibody|Proteoglycan 10K core protein antibody|Proteoglycan peptide core protein antibody|PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE antibody|secretory granule proteoglycan 1 antibody|Secretory granule proteoglycan core peptide antibody|Secretory granule proteoglycan core protein antibody|Serglycin antibody|serglycin proteoglycan antibody|Sgc antibody|Srgn antibody|SRGN_HUMAN antibody
Anti-Serglycin antibody (ab211515)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SRGN Antibody

Catalogue No.

CSB-PA022664ESR2HU

Reactivity

Human

Immunogen

Recombinant human Serglycin protein (28-158AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

17 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5552( Human), Omim:177040( Human), SwissProt:P10124( Human), Unigene:1908( Human)

Protein function

Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization. .

Protein sequence and domain

Belongs to the serglycin family.

Protein post-translational modifications

O-glycosylated; contains chondroitin sulfate and heparan sulfate. .

Protein cellular localization

Cytoplasmic granule . Secreted, extracellular space . Golgi apparatus . Note=Found in mast cell granules and in cytoplasmic granules of cytolytic T lymphocytes from where it is secreted upon cell activation (By similarity). Secreted constitutively by endothelial cells and macrophages (PubMed:11154222). Located to Golgi apparatus during neutrophil differentiation (PubMed:15136585). .

Research area

All research areas>Lymphocyte Signaling>Serglycin
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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