Anti-SRRT Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SRRT Antibody (CSB-PA880129ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Arsenite-resistance protein 2 Antibody,SRRT Antibody,ARS2 Antibody, ASR2 Antibody

More alternative names for the antibody
ARS2 protein antibody|Arsenate resistance protein ARS2 antibody|Arsenite resistance protein 2 antibody|Arsenite resistance protein antibody|Arsenite-resistance protein 2 antibody|ASR2 antibody|MGC126427 antibody|Serrate antibody|Serrate RNA effector molecule antibody|Serrate RNA effector molecule homolog (Arabidopsis) antibody|Serrate RNA effector molecule homolog antibody|SRRT antibody|SRRT_HUMAN antibody
Anti-ARS2 antibody – N-terminal (ab192999)
Close sc-376716|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-SRRT Antibody

Catalogue No.

CSB-PA880129ESR1HU

Reactivity

Human

Immunogen

Recombinant human Serrate RNA effector molecule homolog protein (627-876AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

100 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:463860( Chimpanzee), Entrez Gene:527938( Cow), Entrez Gene:479731( Dog), Entrez Gene:101142030( Gorilla), Entrez Gene:100067574( Horse), Entrez Gene:51593( Human), Entrez Gene:83701( Mouse), Entrez Gene:100620890( Pig), Entrez Gene:713235( Rhesus monkey), Entrez Gene:101123523( Sheep), Entrez Gene:549806( Xenopus tropicalis ), Omim:614469( Human), SwissProt:A4IFB1( Cow), SwissProt:Q9BXP5( Human), SwissProt:Q99MR6( Mouse), SwissProt:Q5R539( Orangutan), SwissProt:B1H1X4( Xenopus laevis), SwissProt:Q6INH5( Xenopus laevis), Unigene:111801( Human), Unigene:387734( Mouse)

Protein function

Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity). .

Protein tissue specificity

Ubiquitously expressed. .

Protein sequence and domain

Belongs to the ARS2 family.

Protein cellular localization

Nucleus, nucleoplasm . Cytoplasm . Note=Predominantly nuclear. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent way (By similarity). .

Research area

All research areas>Signaling Intermediates>ARS2
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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