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Rabbit Anti-STAB2 Antibody (CSB-PA851979ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Stabilin-2 Antibody,FAS1 EGF-like and X-link domain-containing adhesion molecule 2 Antibody,Fasciclin Antibody,EGF-like Antibody,laminin-type EGF-like and link domain-containing scavenger receptor 2 Antibody,FEEL-2 Antibody,Hyaluronan receptor for endocytosis Antibody,STAB2 AntibodyMore alternative names for the antibody
190 kDa form stabilin-2 antibody|190 kDa hyaluronan receptor for endocytosis antibody|EGF-like antibody|FAS1 EGF-like and X-link domain-containing adhesion molecule 2 antibody|Fasciclin antibody|FEEL-2 antibody|FEEL2 antibody|FELL antibody|FEX2 antibody|HARE antibody|Hyaluronan receptor for endocytosis antibody|laminin-type EGF-like and link domain-containing scavenger receptor 2 antibody|link domain-containing scavenger receptor 2 antibody|STAB-2 antibody|Stab2 antibody|STAB2_HUMAN antibody
Anti-Stabilin 2 antibody (ab121893)
Anti-Stabilin 2 antibody (ab121893)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Stabilin-2 protein (1550-1850AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55576" target="_blank">Entrez Gene:55576( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/608561" target="_blank">Omim:608561( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q8WWQ8" target="_blank">SwissProt:Q8WWQ8( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=408249" target="_blank">Unigene:408249( Human)</a>
|Protein function|| |
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS. .
|Protein tissue specificity|| |
Highly expressed in sinusoidal endothelial cells of liver, spleen and lymph nodes. Also expressed in non SEC-cells such as HMDMs (monocyte-derivedmacrophages), HAMs (T-cell leukemia virus type 1-associated myelopathy), and several macrophage cell line. .
|Protein sequence and domain|| |
Recognizes phosphatidyl serine via its epidermal growth factor-like domains.
|Protein post-translational modifications|| |
Glycosylated. .; Proteolytically processed to yield a 190 kDa protein. .
|Protein cellular localization|| |
Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Note=Only a small amount appears to be present at the cell surface (PubMed:17145755).
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Membrane-Receptors/">Membrane Receptors</a>><a href="https://antibodyplus.com/product-tag/HARE/">HARE</a><br><a href="https://antibodyplus.com/product-tag/Membrane-Receptors/"> (View all antibody categories related to Membrane Receptors)</a>
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|Product type|| |
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