Anti-STAM2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-STAM2 Antibody (CSB-PA022793ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Signal transducing adapter molecule 2 Antibody,STAM-2 Antibody,Hrs-binding protein Antibody,STAM2 Antibody,HBP Antibody

More alternative names for the antibody
DKFZp564C047 antibody|Hbp antibody|Hrs-binding protein antibody|HSE1 homolog antibody|Signal transducing adapter molecule 2 antibody|Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody|Signal transducing adaptor molecule 2A antibody|Signal transducing adaptor molecule 2B antibody|Signal transducing adaptor molecule antibody|STAM like protein containing SH3 and ITAM domains 2 antibody|STAM-2 antibody|Stam2 antibody|STAM2_HUMAN antibody|STAM2A antibody|STAM2B antibody
Anti-STAM2 antibody [EPR8688] (ab151545)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-STAM2 Antibody

Catalogue No.

CSB-PA022793ESR2HU

Reactivity

Human

Immunogen

Recombinant human Signal transducing adapter molecule 2 protein (376-525AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

58 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10254( Human), Omim:606244( Human), SwissProt:O75886( Human), Unigene:17200( Human)

Protein function

Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). .

Protein tissue specificity

Ubiquitously expressed. .

Protein sequence and domain

Belongs to the STAM family. The VHS and UIM domains mediate the interaction with ubiquitinated proteins.; The SH3 domain mediates the interaction with USP8.; Contains one Pro-Xaa-Val-Xaa-Leu (PxVxL) motif, which is required for interaction with chromoshadow domains. This motif requires additional residues -7, -6, +4 and +5 of the central Val which contact the chromoshadow domain.

Protein post-translational modifications

Phosphorylated in response to IL-2, GM-CSF, EGF and PDGF.

Protein cellular localization

Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .

Research area

All research areas>Signaling Intermediates>STAM
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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