Anti-STAT4 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-STAT4 Antibody (CSB-PA022813ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

STAT4 Antibody

More alternative names for the antibody

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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-STAT4 Antibody

Catalogue No.

CSB-PA022813ESR1HU

Reactivity

Human

Immunogen

Recombinant human Signal transducer and activator of transcription 4 protein (569-748AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

85 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Protein function

Carries out a dual signal transduction and activation of transcription. Involved in IL12 signaling.

Involvement in disease

Systemic lupus erythematosus 11 (SLEB11) [MIM:612253]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.; Rheumatoid arthritis (RA) [MIM:180300]: An inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the transcription factor STAT family.

Protein post-translational modifications

Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity (By similarity). .

Protein cellular localization

Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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