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Rabbit Anti-STAT4 Antibody (CSB-PA022813ESR1HU)
Supplier: CUSABIO BIOTECH CO.
STAT4 AntibodyMore alternative names for the antibody
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Signal transducer and activator of transcription 4 protein (569-748AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Carries out a dual signal transduction and activation of transcription. Involved in IL12 signaling.
|Involvement in disease|| |
Systemic lupus erythematosus 11 (SLEB11) [MIM:612253]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.; Rheumatoid arthritis (RA) [MIM:180300]: An inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the transcription factor STAT family.
|Protein post-translational modifications|| |
Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity (By similarity). .
|Protein cellular localization|| |
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
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CUSABIO BIOTECH CO.
|Product type|| |
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