Anti-STOML2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-STOML2 Antibody (CSB-PA892131ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Stomatin-like protein 2 Antibody,mitochondrial Antibody,SLP-2 Antibody,EPB72-like protein 2 Antibody,Paraprotein target 7 Antibody,Paratarg-7 Antibody,STOML2 Antibody,SLP2 Antibody,HSPC108 Antibody

More alternative names for the antibody
EPB72 like protein 2 antibody|EPB72-like protein 2 antibody|HSPC108 antibody|OTTHUMP00000021320 antibody|Paraprotein target 7 antibody|Paratarg 7 antibody|SLP 2 antibody|SLP-2 antibody|SLP2 antibody|STML2_HUMAN antibody|Stomatin (EPB72) like 2 antibody|Stomatin like 2 antibody|Stomatin like protein 2 antibody|Stomatin like protein 2, mitochondrial antibody|Stomatin-like protein 2 antibody|STOML2 antibody
Anti-STOML2 antibody [EP18708] (ab191884)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-STOML2 Antibody

Catalogue No.

CSB-PA892131ESR1HU

Reactivity

Human

Immunogen

Recombinant human Stomatin-like protein 2, mitochondrial protein (29-356AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

38 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:30968( Human), Entrez Gene:66592( Mouse), Entrez Gene:298203( Rat), Omim:608292( Human), SwissProt:Q9UJZ1( Human), SwissProt:Q99JB2( Mouse), SwissProt:Q4FZT0( Rat), Unigene:3439( Human), Unigene:331565( Mouse), Unigene:2208( Rat)

Protein function

Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation. .

Protein tissue specificity

Ubiquitously expressed at low levels. Expressed in lymphoid tissues (at protein level). .

Protein sequence and domain

Belongs to the band 7/mec-2 family.

Protein post-translational modifications

Hyperphosphorylated at Ser-17 in some patients with monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma (MM) and Waldenstrom macroglobulinemia due to impaired dephosphorylation by PP2A.

Protein cellular localization

Cell membrane ; Peripheral membrane protein . Mitochondrion . Mitochondrion inner membrane ; Lipid-anchor . Mitochondrion intermembrane space . Membrane raft . Cytoplasm, cytoskeleton . Note=Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain (PubMed:21746876). Also associates with the actin cytoskeleton and membrane rafts in activated T-cells (PubMed:18641330, PubMed:10713127). A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells (PubMed:22623988). .

Research area

All research areas>Synthesis and Degradation>STOML
(View all antibody categories related to Synthesis and Degradation)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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